Related Experiment Video
Updated: Feb 12, 2026

Endoscopic Cholesteatoma Surgery
Published on: January 19, 2022
Comparing the efficacy of Silastic and gloved-Merocel middle meatal spacers for functional endoscopic sinus surgery:
Jamil Manji1, Al-Rahim R Habib1, Luis Macias-Valle1,2
1St. Paul's Sinus Centre, Vancouver, BC, Canada.
Background:
Spacers are inserted into the middle meatal space (MMS) following functional endoscopic sinus surgery (FESS) to prevent lateralization of the middle turbinate, scarring, and synechiae. Our objective was to determine if the incidence of postoperative synechiae, facial pain/discomfort, pain during spacer removal, scarring, and discharge differed between nasal cavities receiving Silastic or gloved-Merocel (GM) spacers following FESS.
Methods:
A double-blind, randomized controlled trial (RCT) was conducted in adults requiring bilateral FESS for chronic rhinosinusitis (CRS) ± nasal polyposis. Participants served as their own controls, with each subject receiving both a Silastic and GM spacer. Spacers were inserted into the MMS during FESS and left in situ for 6 days. Participants were reviewed at 6 days, 5 weeks, and 12 weeks postoperatively. The presence of synechiae and scarring were evaluated endoscopically. Inflammation, discharge, and pain during spacer removal were assessed using a visual analogue scale (VAS).
Results:
Forty-eight participants (96 nasal cavities) were recruited. Preoperatively, Lund-Mackay computed tomography (CT) scores were similar between Silastic-treated and GM-treated cavities (6.38 ± 2.35 vs 6.18 ± 2.17). The incidence of synechiae and scarring did not differ significantly between spacers up to 12 weeks postoperatively. Pain during spacer removal was significantly greater for Silastic than GM spacers (2.13 ± 1.34 vs 1.51 ± 1.23, p = 0.020). Facial pain prior to removal and extent of discharge did not differ significantly between spacers.
Conclusion:
Following FESS, patients report less pain during removal of GM than Silastic spacers. However, the likelihood of synechiae and scarring did not differ between either of the spacers.
Insights
Gloved-Merocel (GM) spacers result in less pain during removal after functional endoscopic sinus surgery (FESS) compared to Silastic spacers. However, both spacer types show similar rates of synechiae and scarring post-FESS.
Area of Science:
- Otolaryngology
- Rhinology
- Surgical Innovation
Background:
- Spacers are crucial post-functional endoscopic sinus surgery (FESS) to prevent middle turbinate lateralization, scarring, and synechiae.
- This study compares Silastic and gloved-Merocel (GM) spacers in the middle meatal space (MMS).
Purpose of the Study:
- To evaluate differences in postoperative synechiae, scarring, facial pain, and discharge between Silastic and GM spacers after FESS.
- To assess pain experienced during spacer removal following FESS.
Main Methods:
- A double-blind, randomized controlled trial (RCT) utilized a within-subject design where patients received both Silastic and GM spacers.
- Spacers were placed in the MMS during FESS and removed after 6 days.
- Outcomes including synechiae, scarring, inflammation, discharge, and pain were assessed using endoscopic evaluation and visual analogue scale (VAS).
Main Results:
- No significant difference in the incidence of synechiae and scarring was observed between Silastic and GM spacers up to 12 weeks postoperatively.
- Patients reported significantly less pain during the removal of GM spacers compared to Silastic spacers (p = 0.020).
- Facial pain before removal and the extent of discharge did not significantly differ between the two spacer types.
Conclusions:
- Gloved-Merocel (GM) spacers are associated with reduced pain during removal compared to Silastic spacers after FESS.
- The choice between Silastic and GM spacers does not impact the likelihood of developing synechiae or scarring post-FESS.
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