Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

What are Lipids?01:38

What are Lipids?

221.2K
Overview
221.2K
What are Lipids?01:31

What are Lipids?

11.4K
Lipids function as structural components of cellular membranes, in addition to acting as energy reservoirs and signaling molecules. They are thus crucial to all living organisms.  The three biologically important classes of lipids are triglycerides, phospholipids, and steroids.
Non-Polar and Hydrophobic Characteristics of Lipids
Lipids are a structurally and functionally diverse group of hydrocarbons—compounds consisting of carbon and hydrogen atoms. The carbon-carbon and...
11.4K
Lipid Digestion01:06

Lipid Digestion

99.8K
Lipids are large molecules that are generally not water-soluble. Since most of the digestive enzymes in the human body are water-based, there are specific steps the body must take to break down lipids and make them available for use.
99.8K
Structure of Lipids03:38

Structure of Lipids

99.2K
Lipids include a diverse group of compounds that are largely nonpolar in nature. This is because they are hydrocarbons that include mostly nonpolar carbon-carbon or carbon-hydrogen bonds. Non-polar molecules are hydrophobic (“water fearing”), or insoluble in water. Lipids perform many different functions in a cell. Cells store energy for long-term use in the form of fats. Lipids also provide insulation from the environment for plants and animals. For example, they help keep aquatic...
99.2K
Lipids as Anchors01:32

Lipids as Anchors

7.4K
In the plasma membrane, the lipids forming the bilayer can also act as an anchor to tether proteins to the membrane. The three main types of lipid anchors found in eukaryotes are – prenyl groups, fatty acyl groups, and glycosylphosphatidylinositol or GPI groups. Prenyl and fatty acyl groups act as anchors on the cytosolic surface of the membrane, whereas GPI anchors proteins on the extracellular side.
The carboxy-terminal of most of the prenylated proteins, such as Ras proteins, contains...
7.4K
Lipid Catabolism01:25

Lipid Catabolism

1.1K
Triglycerides serve as crucial long-term energy storage molecules in microorganisms, providing a dense source of metabolic energy. Their breakdown is mediated by lipases, which hydrolyze triglycerides into glycerol and free fatty acids. Each of these components follows distinct metabolic pathways, ultimately contributing to ATP synthesis and cellular energy homeostasis.Glycerol MetabolismGlycerol, released from triglyceride hydrolysis, is phosphorylated by glycerol kinase to form...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Whole exome sequencing and 12-SNP LDL polygenic score in South Indian patients with familial hypercholesterolemia.

Scientific reports·2026
Same author

Does Adopting Western Low-density Lipoprotein Cholesterol Targets Expose Indians to a Higher Risk of Cardiovascular Events? Expert Opinion From the Lipid Association of India.

The Journal of the Association of Physicians of India·2024
Same author

Lipid Association of India 2023 update on cardiovascular risk assessment and lipid management in Indian patients: Consensus statement IV.

Journal of clinical lipidology·2024
Same author

Assessment of non-alcoholic fatty liver disease (NAFLD) severity with novel serum-based markers: A pilot study.

PloS one·2021
Same author

Management of Dyslipidaemia for the Prevention of Stroke: Clinical Practice Recommendations from the Lipid Association of India.

Current vascular pharmacology·2021
Same author

Lipid Association of India Expert Consensus Statement on Management of Dyslipidemia in Indians 2020: Part III.

The Journal of the Association of Physicians of India·2020

Related Experiment Video

Updated: Feb 12, 2026

Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection
08:15

Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection

Published on: January 31, 2020

9.2K

HIV infection and lipids.

Anjly Jain1, Trupti Kolvekar, Devaki R Nair

  • 1Department of Clinical Biochemistry, Royal Free London NHS Foundation Trust, London, UK.

Current Opinion in Cardiology
|March 31, 2018
PubMed
Summary
This summary is machine-generated.

Dyslipidemia significantly increases cardiovascular disease (CVD) risk in HIV patients due to infection and antiretroviral therapy (ART). Early CVD risk assessment and lipid-friendly ART are crucial for managing HIV-associated CVD.

More Related Videos

Amplifying and Quantifying HIV-1 RNA in HIV Infected Individuals with Viral Loads Below the Limit of Detection by Standard Clinical Assays
13:58

Amplifying and Quantifying HIV-1 RNA in HIV Infected Individuals with Viral Loads Below the Limit of Detection by Standard Clinical Assays

Published on: September 26, 2011

32.2K
Imaging of HIV-1 Envelope-induced Virological Synapse and Signaling on Synthetic Lipid Bilayers
11:45

Imaging of HIV-1 Envelope-induced Virological Synapse and Signaling on Synthetic Lipid Bilayers

Published on: March 8, 2012

12.7K

Related Experiment Videos

Last Updated: Feb 12, 2026

Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection
08:15

Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection

Published on: January 31, 2020

9.2K
Amplifying and Quantifying HIV-1 RNA in HIV Infected Individuals with Viral Loads Below the Limit of Detection by Standard Clinical Assays
13:58

Amplifying and Quantifying HIV-1 RNA in HIV Infected Individuals with Viral Loads Below the Limit of Detection by Standard Clinical Assays

Published on: September 26, 2011

32.2K
Imaging of HIV-1 Envelope-induced Virological Synapse and Signaling on Synthetic Lipid Bilayers
11:45

Imaging of HIV-1 Envelope-induced Virological Synapse and Signaling on Synthetic Lipid Bilayers

Published on: March 8, 2012

12.7K

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Pharmacology

Background:

  • HIV infection and antiretroviral therapy (ART) contribute to dyslipidemia and cardiovascular disease (CVD) risk.
  • Older ART regimens were associated with higher lipid abnormalities, while newer therapies are more lipid-friendly.
  • Increased life expectancy in HIV patients leads to a rise in non-HIV related complications like CVD.

Purpose of the Study:

  • To review the role of dyslipidemia in CVD among HIV-infected patients.
  • To discuss traditional CVD risk factors, HIV-specific risks, and ART-induced dyslipidemia.

Main Methods:

  • Literature review and expert commentary on dyslipidemia in HIV.
  • Analysis of risk factors contributing to CVD in the HIV population.
  • Discussion of current and emerging ART strategies and their lipid impact.

Main Results:

  • HIV patients face complex CVD risk due to infection and ART.
  • Advancements in ART have improved life expectancy but shifted mortality towards non-HIV complications like CVD.
  • Ongoing studies are investigating interventions for dyslipidemia in HIV.

Conclusions:

  • All HIV patients require CVD risk assessment before initiating ART.
  • Selection of lipid-friendly ART regimens is recommended.
  • Intervention for associated CVD risk factors, including lipids, hypertension, and smoking, is essential.