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Updated: Feb 12, 2026
Fabrication of 1-D Photonic Crystal Cavity on a Nanofiber Using Femtosecond Laser-induced Ablation
Published on: February 25, 2017
Optical Biosensors Based on Photonic Crystals Supporting Bound States in the Continuum
Silvia Romano1, Annalisa Lamberti2, Mariorosario Masullo3
1Institute for Microelectronics and Microsystems-Unit of Naples-National Council of Research, Via Pietro Castellino, 80131 Naples, Italy. silvia.romano@na.imm.cnr.it.
Abstract:
A novel optical label-free bio-sensing platform based on a new class of resonances supported in a photonic crystal metasurface is reported herein. Molecular binding is detected as a shift in the resonant wavelength of the bound states in the continuum of radiation modes. The new configuration is applied to the recognition of the interaction between protein p53 and its protein regulatory partner murine double minute 2 (MDM2). A detection limit of 66 nM for the protein p53 is found. The device provides an excellent interrogation stability and loss-free operation, requires minimal optical interrogation equipment and can be easily optimized to work in a wide wavelength range.
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