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Safety of laparoscopic fundoplication in children under 5 kg: a comparative study
Jean-Baptiste Marret1,2, Claire Dupont-Lucas3,4, Thierry Petit5
1Department of Pediatric Surgery, University Hospital of Caen, Avenue de la Côte de Nacre, 14032, Caen Cedex 9, France. marret-jb@chu-caen.fr.
Insights
Laparoscopic fundoplication (LF) is safe and effective in infants weighing 5 kg or less. This study found no increased complications or operative time compared to heavier infants, supporting its use in low-weight infants.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Minimally Invasive Surgery
Background:
- Laparoscopic fundoplication (LF) safety and efficacy in infants under 5 kg remains debated.
- Evaluating LF in this low-weight pediatric population is crucial for clinical practice.
Purpose of the Study:
- To assess the safety and efficacy of laparoscopic fundoplication (LF) in infants weighing 5 kg or less.
- To compare outcomes between low-weight (≤5 kg) and higher-weight (5.1–10 kg) pediatric patients undergoing LF.
Main Methods:
- Retrospective review of 96 pediatric patients undergoing LF between 2005 and 2014.
- Patients were divided into a Low Weight Group (LWG, ≤5 kg) and a High Weight Group (HWG, 5.1–10 kg).
- Comparison of pre-operative, peri-operative, and post-operative data, including surgical and anesthesia parameters.
Main Results:
- Operating times and intraoperative respiratory parameters (PCO2) were comparable between LWG and HWG.
- While LWG infants required more pre-operative respiratory support, post-operative complications were similar between groups.
- GERD recurrence requiring re-operation was noted in 3 LWG patients and 1 HWG patient.
Conclusions:
- Laparoscopic fundoplication is a safe and effective procedure for infants weighing 5 kg or less.
- The procedure does not lead to an increased rate of post-operative complications, recurrence, or operative time in low-weight infants.
- Findings support the use of LF in this vulnerable pediatric population.
Background:
Laparoscopic fundoplication in children under 5 kg is still debated. Our objective was to evaluate the safety and efficacy of laparoscopic fundoplication (LF) in children under 5 kg.
Methods:
We reviewed the cases of 96 children treated by laparoscopic fundoplication between 2005 and 2014. Thirty-five patients had a weight of 5 kg or less at the time of LF (Low Weight Group) and 61 patients had a weight between 5.1 and 10 kg (High Weight Group). The pre-operative, peri-operative, post-operative data regarding surgery and anesthesia were compared between groups.
Results:
Mean weight was 3.9 ± 0.8 kg in the LWG and 7.8 ± 1.5 kg in the HWG. Children in the LWG were more prone to pre-operative respiratory management (40% mechanical ventilation and 42.9% oxygen therapy). The operating times (82 ± 28 min for LWG and 85 ± 31 min for HWG) and respiratory parameters during the procedure (PCO2) were comparable between groups. Post-operative complications were 1 gastric perforation with peritonitis and 1 small bowel obstruction in the LWG, 2 cases of gastric perforation with peritonitis in the HWG. Mean follow-up was 67 ± 44 months. Significant recurrence of GERD requiring a redo fundoplication was noted in 3 patients in the LWG and 1 patient in the HWG.
Conclusion:
Laparoscopic fundoplication is a safe procedure in infants ≤ 5 kg without increase of post-operative complications, recurrence, or mean operative time.
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