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Annexins--new family of Ca2+-regulated-phospholipid binding protein
M J Geisow1, J H Walker, C Boustead
1Protein Chemistry, Delta Biotechnology Ltd., Nottingham.
Bioscience Reports
|April 1, 1987
Abstract:
Calcium and phospholipid binding proteins have been identified and localized by immunocytochemistry in a wide range of cells and tissues. Two of these proteins (calpactins) also bind F-actin and are substrates for tyrosine kinases. The similar membrane-binding properties of these molecules arise from conserved amino acid sequences and a model is proposed for the tertiary structure of a common calcium and phospholipid binding domain.