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Related Experiment Video

Updated: Feb 12, 2026

P50 Sensory Gating in Infants

P50 Sensory Gating in Infants

Published on: December 26, 2013

Multiple functional gastrointestinal disorders are frequent in formula-fed infants and decrease their quality of

Marc Bellaiche¹, Raish Oozeer², Geraldine Gerardi-Temporel²

¹GI Unit, Robert Debré Hospital, Paris, France.

Acta Paediatrica (Oslo, Norway : 1992)

|April 1, 2018

Summary

Combined functional gastrointestinal disorders (FGIDs) are common in infants, negatively impacting breastfeeding, weight gain, and quality of life (QoL). Early identification and management are crucial for infant well-being.

Keywords:

Bloating Colic Intestinal gas Quality of life Regurgitation

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Area of Science:

Pediatrics
Gastroenterology
Infant Health

Background:

Functional gastrointestinal disorders (FGIDs) are prevalent in infants.
Understanding the incidence and impact of combined FGIDs is crucial for early intervention.

Purpose of the Study:

To evaluate the incidence of functional gastrointestinal disorders (FGIDs) in infants, both individually and in combination.
To assess the impact of combined FGIDs on infant health outcomes and quality of life (QoL).

Main Methods:

Prospective study involving 2757 infants aged 0-6 months.
Assessment of FGIDs using Rome III criteria and monitoring of Quality of Life (QoL) via questionnaires.
Data collected by 273 French pediatricians from March 2013 to January 2014.

Main Results:

Combined FGIDs diagnosed in 78% of infants; 63% had two, 15% had three or more.
Frequent combinations included gas/bloating and colic (28%), colic and regurgitation (17%), and gas/bloating and regurgitation (8%).
Combined FGIDs correlated with lower body weight, shorter breastfeeding duration, decreased QoL, and increased drug prescriptions.

Conclusions:

Combined FGIDs are highly prevalent in infants up to six months.
Combined FGIDs negatively affect breastfeeding, weight gain, and infant QoL.
Infants with combined FGIDs showed greater QoL improvements post-intervention.