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Nasal saline irrigation in pediatric rhinosinusitis: A systematic review
Jean-Nicolas Gallant1, Jade I Basem2, Justin H Turner3
1School of Medicine, United States.
Insights
Nasal saline irrigation (NSI) may help children with acute rhinosinusitis (ARS) symptoms. More research is needed to confirm its effectiveness, especially for chronic rhinosinusitis (CRS) in children.
Area of Science:
- Pediatric Otolaryngology
- Respiratory Medicine
- Evidence-Based Medicine
Background:
- Rhinosinusitis is common in children, affecting quality of life.
- Acute (ARS) and chronic (CRS) rhinosinusitis present distinct clinical challenges.
- Nasal saline irrigation (NSI) is a potential non-pharmacological treatment option.
Purpose of the Study:
- To evaluate the efficacy of NSI for symptom reduction in pediatric ARS and CRS.
- To assess the impact of NSI on quality of life in pediatric rhinosinusitis patients.
- To identify the current evidence base for NSI in pediatric rhinosinusitis.
Main Methods:
- Systematic literature search of PubMed/MEDLINE and Embase databases (1950-2017).
- Inclusion criteria focused on studies of NSI in pediatric patients with ARS or CRS.
- Analysis of symptom scores and parental surveys; two independent reviewers assessed articles.
Main Results:
- Only one study met inclusion criteria, focusing on NSI for pediatric ARS.
- No studies on NSI for pediatric CRS were identified.
- Included studies showed symptom improvement with NSI, but heterogeneity in methods hindered meta-analysis.
Conclusions:
- NSI shows potential benefit for acute rhinosinusitis in children.
- Further high-quality research with standardized outcome measures is required.
- Efficacy of NSI for pediatric chronic rhinosinusitis remains undetermined.
Objective:
To determine the efficacy of nasal saline irrigation (NSI) in reducing symptoms and improving quality of life in pediatric patients with acute (ARS) or chronic (CRS) rhinosinusitis.
Data Sources:
We searched the PubMed/MEDLINE and Embase electronic databases (indexed January, 1950 through April, 2017).
Review Methods:
Studies assessing the efficacy of NSI in pediatric patients with ARS or CRS were selected for analysis. Outcome measures, including symptom scores and parental surveys, were analyzed. Two independent reviewers evaluated each abstract and article.
Results:
Of the 272 articles identified using our search strategy, only 1 study, focusing on the use of NSI in pediatric ARS, met all inclusion criteria. No studies investigating NSI in pediatric CRS were included for analysis. In general, studies demonstrated significant improvement of symptom scores with the use of NSI in pediatric rhinosinusitis; but, the use of varied outcome measures, control treatments, and NSI delivery made including studies and drawing conclusions difficult. No quantitative meta-analysis could be performed.
Conclusion:
NSI may provide benefit for ARS in children; however, additional high-quality studies with defined outcome measures are needed to determine the quantitative efficacy of this therapy in the pediatric patients with rhinosinusitis-especially in pediatric CRS.
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