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Related Concept Videos

Spinal Cord01:26

Spinal Cord

2.0K
The spinal cord, a critical component of the central nervous system, extends from the base of the brainstem to the lumbar region of the vertebral column. It is essential for maintaining physical stability and facilitating communication between the brain and peripheral parts of the body.
2.0K
The Spinal Cord01:54

The Spinal Cord

31.9K
The spinal cord is the body’s major nerve tract of the central nervous system, communicating afferent sensory information from the periphery to the brain and efferent motor information from the brain to the body. The human spinal cord extends from the hole at the base of the skull, or foramen magnum, to the level of the first or second lumbar vertebra.
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Spinal Cord: Information Processing01:10

Spinal Cord: Information Processing

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The spinal cord is an integral hub for motor and sensory information that enables the brain to communicate with the peripheral nervous system (PNS). This communication consists of relaying sensory data and transmission of motor commands.
Sensory Information Processing
Sensory information processing begins at the sensory receptors located in the skin and other tissues, which detect somatic sensory stimuli such as touch, temperature, or pain. These receptors function as catalysts, initiating...
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Spinal Cord: Gross Anatomy01:15

Spinal Cord: Gross Anatomy

5.9K
The spinal cord resides within the protective confines of the vertebral column. It is the main pathway for information traveling between the brain and the body. It plays a fundamental role in nearly all bodily functions, from simple reflexes to complex motor movements. The spinal cord begins at the medulla oblongata at the base of the brainstem and extends downward, terminating at the conus medullaris near the first and second lumbar vertebrae. The spinal cord's length in adults is...
5.9K
Spinal Cord: Cross-sectional Anatomy01:16

Spinal Cord: Cross-sectional Anatomy

4.9K
The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
Gray Matter and its Components
Central to the gray matter is...
4.9K
Intrinsically Disordered Proteins02:18

Intrinsically Disordered Proteins

19.6K
Intrinsically disordered proteins are a group of proteins that do not fold into specific three-dimensional structures. Their structural flexibility allows them to complement ordered proteins to perform functions that are inaccessible to rigid structures. They are more common in eukaryotes than prokaryotes and may either be exclusively intrinsically disordered or hybrid proteins, consisting of a mix of ordered and disordered regions. The absence of a rigid structure in these proteins can be...
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Related Experiment Video

Updated: Feb 12, 2026

Paradigms of Lower Extremity Electrical Stimulation Training After Spinal Cord Injury
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Paradigms of Lower Extremity Electrical Stimulation Training After Spinal Cord Injury

Published on: February 1, 2018

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Spinal Cord Disorders: Myelopathy.

Shamik Bhattacharyya1

  • 1Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass.

The American Journal of Medicine
|April 2, 2018
PubMed
Summary

Myelopathy is diagnosed clinically, with imaging like MRI aiding in identifying causes. In older adults, compressive myelopathy due to vertebral degeneration is most common and should be investigated first.

Area of Science:

  • Neurology
  • Clinical Diagnosis
  • Medical Imaging

Background:

  • Myelopathy presents with clinical symptoms and physical findings.
  • Diagnostic tools like laboratory tests and magnetic resonance imaging (MRI) help determine the cause.
  • Compressive myelopathy from vertebral degenerative disease is the leading cause in older adults.

Purpose of the Study:

  • To outline the diagnostic approach to myelopathy.
  • To emphasize the importance of considering compressive myelopathy in the elderly.
  • To highlight the diverse etiologies of myelopathy.

Main Methods:

  • Clinical assessment of symptoms and physical examination.
  • Utilizing laboratory investigations.
  • Employing magnetic resonance imaging (MRI) for etiological diagnosis.
Keywords:
MyelitisMyelopathySpinal cordSpinal cord anatomy

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Acute and Chronic Tactile Sensory Testing after Spinal Cord Injury in Rats
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Acute and Chronic Tactile Sensory Testing after Spinal Cord Injury in Rats

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Evaluation of Respiratory Muscle Activation Using Respiratory Motor Control Assessment RMCA in Individuals with Chronic Spinal Cord Injury
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Evaluation of Respiratory Muscle Activation Using Respiratory Motor Control Assessment RMCA in Individuals with Chronic Spinal Cord Injury

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Related Experiment Videos

Last Updated: Feb 12, 2026

Paradigms of Lower Extremity Electrical Stimulation Training After Spinal Cord Injury
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Paradigms of Lower Extremity Electrical Stimulation Training After Spinal Cord Injury

Published on: February 1, 2018

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Acute and Chronic Tactile Sensory Testing after Spinal Cord Injury in Rats
08:57

Acute and Chronic Tactile Sensory Testing after Spinal Cord Injury in Rats

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Evaluation of Respiratory Muscle Activation Using Respiratory Motor Control Assessment RMCA in Individuals with Chronic Spinal Cord Injury
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Main Results:

  • Myelopathy diagnosis relies on clinical presentation.
  • MRI is crucial for identifying the cause of myelopathy.
  • Degenerative compressive myelopathy is the most frequent cause in the elderly.

Conclusions:

  • Clinical evaluation is the cornerstone of myelopathy diagnosis.
  • Screening for compressive myelopathy is essential in older patients.
  • A broad differential diagnosis including infectious, immune, nutritional, vascular, and neoplastic causes is necessary.