Variability in the time to initiation of CPR in continuously monitored pediatric ICUs

M Olson1, E Helfenbein2, L Su1

  • 1Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.

Resuscitation
|April 2, 2018
PubMed

Insights

Nearly half of pediatric ICU patients experienced delays in cardiopulmonary resuscitation (CPR) initiation after cardiac arrest (CPA), missing American Heart Association guidelines. Further study of CPA recognition is needed to improve timeliness.

Area of Science:

  • Pediatric Critical Care Medicine
  • Cardiovascular Research
  • Health Systems Science

Background:

  • Delays in cardiopulmonary resuscitation (CPR) initiation following pediatric cardiac arrest (CPA) can negatively impact patient outcomes.
  • Understanding factors influencing the time from CPA to CPR is crucial for improving pediatric intensive care unit (ICU) care.

Purpose of the Study:

  • To investigate patient characteristics and unit ergonomics influencing the time to CPR initiation in pediatric ICU patients.
  • To identify potential areas for improving the recognition and response to CPA in critically ill children.

Main Methods:

  • A single-center study analyzed continuous monitoring data (ECG, plethysmography, blood pressure, EtCO2) in children (0-21 years) experiencing CPA requiring >1 minute of chest compressions.
  • CPR initiation was identified by ECG artifact. Patient factors (CPA cause, High-Risk Checklist identification, monitoring) and unit factors (ICU type, time of day, shift change) were examined.

Main Results:

  • The median time from CPA to CPR initiation was 50.5 seconds (IQR 26.5-127.5) in 36 events.
  • Forty-seven percent of patients experienced a delay of >1 minute from CPA to CPR initiation.
  • No significant differences in delay were observed based on CPA cause, ICU type, time of day, or nursing shift change.

Conclusions:

  • A significant proportion of pediatric ICU patients experiencing CPA do not receive CPR within recommended timeframes.
  • Continuous monitoring data offers an opportunity to better understand CPA recognition and factors contributing to delayed CPR.
  • Improving the recognition phase of CPA is essential for enhancing adherence to early CPR guidelines in pediatric ICUs.
Abstract

Related Concept Videos

Continuous -time Fourier Transform01:11

Continuous -time Fourier Transform

The Fourier series is instrumental in representing periodic functions, offering a powerful method to decompose such functions into a sum of sinusoids. This technique, however, necessitates modification when applied to nonperiodic functions. Consider a pulse-train waveform consisting of a series of rectangular pulses. When these pulses have a finite period, they can be accurately represented by a Fourier series. Yet, as the period approaches infinity, resulting in a single, isolated pulse, the...
925
Basic Continuous Time Signals01:22

Basic Continuous Time Signals

Basic continuous-time signals include the unit step function, unit impulse function, and unit ramp function, collectively referred to as singularity functions. Singularity functions are characterized by discontinuities or discontinuous derivatives.
The unit step function, denoted u(t), is zero for negative time values and one for positive time values, exhibiting a discontinuity at t=0. This function often represents abrupt changes, such as the step voltage introduced when turning a car's...
724
Sampling Continuous Time Signal01:11

Sampling Continuous Time Signal

In signal processing, a continuous-time signal can be sampled using an impulse-train sampling technique, followed by the zero-order hold method. Impulse-train sampling involves the use of a periodic impulse train, which consists of a series of delta functions spaced at regular intervals determined by the sampling period. When a continuous-time signal is multiplied by this impulse train, it generates impulses with amplitudes corresponding to the signal's values at the sampling points.
In the...
764
Initiation of Translation02:33

Initiation of Translation

Initiating translation is complex because it involves multiple molecules. Initiator tRNA, ribosomal subunits, and eukaryotic initiation factors (eIFs) are all required to assemble on the initiation codon of mRNA. This process consists of several steps that are mediated by different eIFs.
First, the initiator tRNA must be selected from the pool of elongator tRNAs by eukaryotic initiation factor 2 (eIF2). The initiator tRNA (Met-tRNAi) has conserved sequence elements including modified bases at...
39.2K
Initiation of Translation02:33

Initiation of Translation

8.2K
BIBO stability of continuous and discrete -time systems01:24

BIBO stability of continuous and discrete -time systems

System stability is a fundamental concept in signal processing, often assessed using convolution. For a system to be considered bounded-input bounded-output (BIBO) stable, any bounded input signal must produce a bounded output signal. A bounded input signal is one where the modulus does not exceed a certain constant at any point in time.
To determine the BIBO stability, the convolution integral is utilized when a bounded continuous-time input is applied to a Linear Time-Invariant (LTI) system....
946