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Angiolymphoid hyperplasia with eosinophilia: a case report
Alexey Youssef1, Ali Ramez Hasan2, Youssef Youssef3
1Faculty of Medicine, Tishreen University, Lattakia, Syria. alexeyyousef1994@gmail.com.
Journal of Medical Case Reports
|April 3, 2018
Summary
Angiolymphoid hyperplasia with eosinophilia (AH E) is a rare condition presenting a therapeutic challenge. A case of a young girl with nasal masses highlights the difficulties in managing this benign neoplasm.
Area of Science:
- Dermatology
- Pathology
- Oncology
Background:
- Angiolymphoid hyperplasia with eosinophilia (AH E) is a benign vascular neoplasm.
- Characterized by blood vessel proliferation and eosinophilic inflammation.
- Typically affects middle-aged adults on the ear or periauricular area.
Observation:
- A 13-year-old girl presented with large, bilateral, yellowish nostril masses.
- The unusual location and appearance posed diagnostic and therapeutic challenges.
- Initial treatments with oral and topical steroids, and indomethacin were ineffective.
Findings:
- Diagnosis of angiolymphoid hyperplasia with eosinophilia was confirmed.
- The condition was resistant to standard therapies, including multiple surgical excisions.
- A combination of intralesional steroids and topical tacrolimus showed partial control.
Implications:
- AH E presents a significant therapeutic dilemma due to varied treatment responses.
- Disfiguring lesions impact patient quality of life, necessitating further research.
- Development of effective, unified treatment strategies for AH E is crucial.
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