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Understanding Primate Herpesviruses

R Eberle1, L Jones-Engel2

  • 1Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Oklahoma, USA.

Journal of Emerging Diseases and Virology
|April 3, 2018
PubMed

Insights

Herpes B virus (BV) is common in macaques but rarely causes illness. However, it can be severe or fatal in non-native hosts, highlighting the importance of understanding its transmission and treatment.

Area of Science:

  • Virology
  • Primate Health
  • Zoonotic Diseases

Background:

  • Herpes B virus (BV) is prevalent in macaques, with documented cross-species transmission.
  • While typically asymptomatic in macaques, BV can cause severe, fatal disease in non-native hosts if untreated.

Purpose of the Study:

  • To provide a comprehensive review of Herpes B virus (BV).
  • To summarize knowledge on related nonhuman primate (NHP) herpesviruses and their zoonotic potential.

Main Methods:

  • Literature review of taxonomy, molecular biology, physiology, epidemiology, diagnosis, and treatment of BV.
  • Synthesis of information on related NHP herpesviruses.

Main Results:

  • BV is widespread in macaques and can transmit across species.
  • Untreated BV infection in non-native hosts can lead to severe or fatal outcomes.

Conclusions:

  • A thorough understanding of BV's characteristics is crucial for managing its zoonotic risks.
  • Further research into related NHP herpesviruses is needed to assess broader public health implications.
Keywords:
AtHV1AtelineBVCercopithecineChHVHSV1HSV2HVA1HVP2HVS1Herpes BMacacaMacacine herpesvirus 1MacaquesPapiinePrimatesSA8Sahv1Saimirineα-Herpesviruses

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