Prolonged toxicity from Kambo cleansing ritual.

Area of Science:

• Ethnobotany
• Toxicology
• Integrative Medicine

Background:

• Kambo cleanse is a traditional South American shamanic ritual involving topical application of secretions from the giant leaf frog (Phyllomedusa bicolor).
• The practice is purported to confer luck and health, and is gaining popularity in Europe and the USA.
• The ritual involves inducing intense gastrointestinal symptoms for purported benefits like increased stamina.

Observation:

• A patient presented with prolonged vomiting, flushing, facial swelling, altered mental status, and agitation 22 hours post-Kambo cleanse.
• Physical examination revealed four superficial burns on the ankle, consistent with resin application sites.
• The patient required chemical restraints due to agitation and altered mental status.

Findings:

• The Kambo cleanse involves introducing frog secretions into superficial wounds, causing significant physiological responses.
• Adverse effects can be severe and prolonged, necessitating emergency medical intervention.
• The case demonstrates a potential disconnect between traditional use and modern medical understanding of Kambo's effects.

Implications:

• Healthcare providers should be aware of Kambo cleanse and its potential adverse effects.
• Further research is needed to understand the toxicology and physiological impact of Phyllomedusa bicolor secretions.
• Patients considering Kambo cleanse should be informed of the associated health risks.