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A model of two conformational forms of heparins/heparans suggested by infrared spectroscopy
D Grant1, W F Long, F B Williamson
1Department of Biochemistry, University of Aberdeen, Marischal College, U.K.
Medical Hypotheses
|October 1, 1987
Abstract:
Results of infrared spectroscopy of complexes between cations and heparins, heparans and chemically-modified polymers suggest the existence of two conformational forms of heparins/heparans, differing in their modes of interaction with cations. Functions of heparans at normal and cancer cell surfaces are discussed in the light of this model.