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Computerized tomography in amyotrophic choreo-acanthocytosis.

S Serra¹, A Xerra, E Scribano

¹Institute of Neurological and Neurosurgery Sciences, Messina University, Italy.

|January 1, 1987

Summary

Computed tomography (CT) confirmed caudate nuclei atrophy in amyotrophic choreo-acanthocytosis (ACA) patients. However, CT findings were similar to Huntington

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Area of Science:

Neurology
Radiology
Genetics

Background:

Amyotrophic choreo-acanthocytosis (ACA) is a rare neurodegenerative disorder.
Caudate nuclei atrophy is a known feature in ACA.

Purpose of the Study:

To evaluate CT findings in ACA patients.
To compare CT measurements with those in Huntington's chorea.

Main Methods:

Computed tomography (CT) scans were analyzed in five ACA patients.
Bicaudate diameter, bicaudate index, and frontal horn/bicaudate ratio (FH/CC) were measured.

Main Results:

CT findings confirmed caudate nuclei atrophy in ACA patients.
CT measurements in ACA did not differ significantly from Huntington's chorea.

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No correlation was found between CT measurements and age, illness duration, or hyperkinesia severity in ACA.

Conclusions:

CT can visualize caudate nuclei atrophy in ACA.
ACA's CT presentation is similar to Huntington's chorea.
Unlike Huntington's chorea, CT measurements in ACA do not correlate with clinical parameters.