Long-term effects on cardiovascular risk of a structured multidisciplinary lifestyle program in clinical practice

Matthias Lidin1,2, Mai-Lis Hellénius3,4, Monica Rydell-Karlsson5,6

  • 1Karolinska Institutet, Department of Medicine, Stockholm, Sweden. matthias.lidin@ki.se.

Insights

A lifestyle program significantly improved cardiovascular risk factors like obesity and hypertension over one year. This multidisciplinary approach reduced overall cardiovascular risk in participants with increased risk.

Area of Science:

  • Cardiology
  • Preventive Medicine
  • Public Health

Background:

  • Cardiovascular disease (CVD) remains a primary cause of global premature mortality.
  • Key etiological factors include abdominal obesity, hypertension, and dyslipidemia.
  • Individuals with elevated cardiovascular risk require effective interventions.

Purpose of the Study:

  • To evaluate the impact of a multidisciplinary lifestyle program on cardiovascular risk factors.
  • To assess changes in overall cardiovascular risk after 6 months and 1 year.
  • To determine the program's effectiveness in a clinical setting for high-risk individuals.

Main Methods:

  • A prospective study involving 100 individuals with increased cardiovascular risk.
  • Intervention included individual consultations, health check-ups, and group educational sessions over 1 year.
  • Cardiovascular risk was quantified using the Framingham cardiovascular risk prediction model.

Main Results:

  • Significant reductions observed in waist circumference, blood pressure, and total cholesterol after 1 year.
  • Overall cardiovascular risk decreased by 15% based on the Framingham 10-year risk prediction model.
  • Benefits were consistent across genders and among participants with or without prior cardiovascular disease.

Conclusions:

  • A structured, year-long lifestyle program effectively improves multiple cardiovascular risk factors.
  • The intervention leads to a significant reduction in overall cardiovascular risk.
  • This approach demonstrates clinical utility in managing individuals at high cardiovascular risk.
Abstract

Related Concept Videos

Introduction to Stress and Lifestyle01:27

Introduction to Stress and Lifestyle

Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...
660
Lifestyle Factors and Health01:20

Lifestyle Factors and Health

Lifestyle factors play a critical role in maintaining overall health and preventing chronic diseases. Key elements, such as regular physical activity, a nutritious diet, and abstinence from smoking, can significantly enhance physical, mental, and emotional well-being while reducing the risk of several life-threatening conditions.
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...
506
Relative Risk01:12

Relative Risk

Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
2.2K
Long-term Depression01:05

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
33.4K
Overview of the Cardiovascular System01:14

Overview of the Cardiovascular System

The cardiovascular system is a vital transportation system in the body. It comprises the heart and blood vessels and facilitates the exchange of gases, nutrients, and waste products.
Heart
The heart is the central pump of the cardiovascular system that circulates blood throughout the body. It comprises two atria receiving the blood and two ventricles pumping blood out of the heart. Their rhythmic contractions, called heartbeats, ensure that blood flow remains continuous.
Blood Vessels
Blood...
12.2K
Structure of Lipids03:38

Structure of Lipids

Lipids include a diverse group of compounds that are largely nonpolar in nature. This is because they are hydrocarbons that include mostly nonpolar carbon-carbon or carbon-hydrogen bonds. Non-polar molecules are hydrophobic (“water fearing”), or insoluble in water. Lipids perform many different functions in a cell. Cells store energy for long-term use in the form of fats. Lipids also provide insulation from the environment for plants and animals. For example, they help keep aquatic...
99.2K