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Epileptogenicity and pathology - Under consideration of ablative approaches
1Department of Neurology - Biomagnetism, University Hospital Erlangen, 10, Schwabachanlage, 91054 Erlangen, Germany.
Abstract:
Besides resective epilepsy surgery, minimally invasive ablation using new diagnostic and therapeutic techniques recently became available. Optimal diagnostic approaches for these treatment options are discussed. The pathophysiology of epileptogenic networks differs depending on the lesion-types and location, requiring a differential use of non-invasive or invasive functional studies. In addition to the definition of epileptogenic zones, a challenge for pre-surgical investigation is the determination of three-dimensional epileptic networks to be removed.
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