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Updated: Jul 19, 2026

Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia
08:38

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[Experiences with Depo-Provera (medroxyprogesterone) in the treatment of kidney tumors]

F Balogh1, I Romics

  • 1Urologische Klinik, Medizinischen Universität Semmelweis, Budapest.

Zeitschrift Fur Urologie Und Nephrologie
|August 1, 1987
PubMed

Insights

Medroxyprogesterone acetate (Depo-Provera) showed promising results in renal tumor patients. No tumor progression deaths occurred in patients without distant metastases, and some distant metastases showed regression or halted progression.

Area of Science:

  • Oncology
  • Pharmacology

Context:

  • Renal tumors represent a significant clinical challenge.
  • Medroxyprogesterone acetate (Depo-Provera) is a progestin with potential anti-cancer properties.

Purpose:

  • To evaluate the efficacy of Medroxyprogesterone acetate in patients with renal tumors.

Summary:

  • Thirty patients with renal tumors received Medroxyprogesterone acetate treatment.
  • In 21 patients without distant metastases, no tumor progression was observed within 6-15 months post-surgery.
  • Among 9 patients with distant metastases, one experienced regression, and another showed halted progression of liver metastases.

Impact:

  • Medroxyprogesterone acetate may offer a therapeutic option for managing renal tumors, particularly in preventing progression.
  • Further research is warranted to explore its role in advanced renal cell carcinoma.

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