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Significant expression of Foxp3 in murine extrathymic CD4+CD8+ double positive T cells

I Gregorczyk1, T Maślanka1

  • 1Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Warmia and Mazury, Oczapowski Street 13, 10-718 Olsztyn, Poland.

Polish Journal of Veterinary Sciences
|April 4, 2018
PubMed
Summary

Murine extrathymic double-positive (DP) T cells express Forkhead box protein 3 (Foxp3), a key marker for regulatory T (Treg) cells. These DP cells resemble CD4+ T cells in Foxp3 expression, suggesting a unique regulatory T cell subset.

Keywords:
CD25, Foxp3CD4+CD8+ double-positive (DP) T cellsTreg cellsmouse

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