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Related Concept Videos

Spinal Cord01:26

Spinal Cord

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The spinal cord, a critical component of the central nervous system, extends from the base of the brainstem to the lumbar region of the vertebral column. It is essential for maintaining physical stability and facilitating communication between the brain and peripheral parts of the body.
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The Spinal Cord01:54

The Spinal Cord

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The spinal cord is the body’s major nerve tract of the central nervous system, communicating afferent sensory information from the periphery to the brain and efferent motor information from the brain to the body. The human spinal cord extends from the hole at the base of the skull, or foramen magnum, to the level of the first or second lumbar vertebra.
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Spinal Cord: Information Processing01:10

Spinal Cord: Information Processing

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The spinal cord is an integral hub for motor and sensory information that enables the brain to communicate with the peripheral nervous system (PNS). This communication consists of relaying sensory data and transmission of motor commands.
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Sensory information processing begins at the sensory receptors located in the skin and other tissues, which detect somatic sensory stimuli such as touch, temperature, or pain. These receptors function as catalysts, initiating...
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Spinal Cord: Gross Anatomy01:15

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The spinal cord resides within the protective confines of the vertebral column. It is the main pathway for information traveling between the brain and the body. It plays a fundamental role in nearly all bodily functions, from simple reflexes to complex motor movements. The spinal cord begins at the medulla oblongata at the base of the brainstem and extends downward, terminating at the conus medullaris near the first and second lumbar vertebrae. The spinal cord's length in adults is...
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Spinal Cord: Cross-sectional Anatomy01:16

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The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
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Central to the gray matter is...
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Traumatic Memory01:20

Traumatic Memory

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Emotionally traumatic events often lead to memories that are exceptionally vivid and enduring, sometimes persisting with remarkable clarity throughout an individual's life. A classic example of this phenomenon is a person who survives a car accident. Even years later, they may recall every detail of the event with startling accuracy — the screeching of the tires, the jarring impact, and the acrid smell of burning rubber. Such vividness contrasts sharply with how an individual...
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Training Persons with Spinal Cord Injury to Ambulate Using a Powered Exoskeleton
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Traumatic Spinal Cord Injury.

Alejandro A Rabinstein

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    Summary
    This summary is machine-generated.

    This review updates acute and subacute management for traumatic spinal cord injury (SCI). Current treatment is supportive, with poor prognosis for severe cases, emphasizing future research in prevention and neuroregeneration.

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    Area of Science:

    • Neuroscience
    • Traumatology
    • Critical Care Medicine

    Background:

    • Traumatic spinal cord injury (SCI) management requires individualized approaches.
    • Current critical care focuses on oxygenation, perfusion, and preventing systemic complications.
    • High-dose methylprednisolone is no longer recommended due to adverse effects.

    Purpose of the Study:

    • To provide an update on the acute and subacute management of traumatic spinal cord injury.
    • To discuss prognostication strategies for patients with traumatic SCI.
    • To highlight future directions in SCI research and treatment.

    Main Methods:

    • Review of current literature on traumatic spinal cord injury management.
    • Analysis of acute and subacute treatment protocols.
    • Evaluation of prognostication factors and outcomes.

    Main Results:

    • Spine immobilization and clearance must be individualized based on neurological exam, pain, and imaging.
    • Early surgical decompression and stabilization (within 24 hours) may improve outcomes.
    • No neuroprotective treatments have demonstrated improved outcomes; methylprednisolone is discouraged.
    • Severe traumatic SCI often results in significant long-term functional impairment.

    Conclusions:

    • Traumatic spinal cord injury treatment remains primarily supportive with a poor prognosis for severely affected individuals.
    • Future research should prioritize injury prevention and the development of effective neuroregenerative therapies.
    • Stem cell transplantation offers future hope but is currently investigational.