Related Experiment Video
Updated: Feb 12, 2026

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
Published on: December 15, 2014
Whole-lesion Apparent Diffusion Coefficient First- and Second-Order Texture Features for the Characterization of
Weifeng Li, Zhuoran Jiang, Yue Guan
1Department of Radiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Objective:
The objective of this study was to explore the value of whole-volume apparent diffusion coefficient (ADC) features in characterizing pathologic features of rectal cancer.
Methods:
A total of 50 patients who were diagnosed with rectal cancer via biopsy underwent 3-T pretreatment diffusion-weighted imaging. Apparent diffusion coefficient features, including mean, 10th-90th percentile, Entropy and Entropy(H), derived from whole-lesion volumes were compared between pathologic T1-2 and T3 stages, perineural invasion (PNI) present and absent, lymphangiovascular invasion present and absent, and pathological N0 and N+ stage groups.
Results:
Entropy and Entropy(H) were significantly lower in rectal cancers at T1-2 stages than T3. The 90th percentile of rectal cancers with PNI was significantly lower than that of those without PNI. All P < 0.05.
Conclusions:
Whole-lesion ADC Entropy and Entropy(H) have potential in evaluating different T stages, and 90th percentile can be helpful for determining PNI presence of rectal cancers.
More Related Videos
Related Concept Videos
Factors Affecting Activity Coefficient
The activity coefficient value for an ion is close to one when the solution has almost zero ionic strength, i.e., when the solution shows close to ideal behavior. As the ionic strength of the solution increases from 0 to 0.1 mol/L, a...
Apparent Weight
Consider a person standing on a bathroom scale inside an elevator. If the scale is accurate at rest, its reading equals the...
Diffusion
Shape and Texture of Coarse Aggregate
Coefficient of Variation
The coefficient of variation is a practical statistical tool in finance. It allows investors to assess the volatility or...
Apparent Weight and the Earth's Rotation
For an object on the Earth's equator, the net centripetal force that accounts for its rotation is the Earth's pull towards its center, or the weight minus the normal force that prevents it from piercing into the Earth's surface....

