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Updated: Feb 12, 2026

The Miniature Pig: A Large Animal Model for Cochlear Implant Research
Published on: July 28, 2022
[Reorganization of central cross-model pattern after auditory deprivation and cortical reconstruction following
1Department of Otorhinolaryngology Head and Neck Surgery, Peking University First Hospital, Beijing100034, China.
Abstract:
The auditory nervous system has a rapid development period after birth, if there lack enough sensory(auditory) stimulation during this period, there should be a serious and negative impact on the growth and development of auditory center. In the auditory deprivation persist in the critical period, the auditory and visual cortex should be in cross-model reorganization and reorientation of cortical function. Cochlear implantation, especially intervention in the younger age, could excite the auditory cortex, and continuous stimulation to the cerebral cortex can promote the adaptation and reconstruction of auditory function. Speech and language skills can be developed by the synergistic effect of multiple sensory modalities.
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