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Published on: July 21, 2023
Next-generation small molecule therapies for heart failure: 2015 and beyond
Justin T Malinowski1, David J St Jean1
1Amgen Discovery Research, 360 Binney St., Cambridge, MA 02142, USA.
Abstract:
Poor prognosis coupled with significant economic burden makes heart failure (HF) one of the largest issues currently facing the world population. Although a significant number of new therapies have emerged over the past 20 years to treat the underlying physiological risk factors, only two new medications specifically for HF have been approved since 2007. This perspective provides an overview of recently approved treatment options for HF and as well as an update on additional small molecule therapies currently in clinical development.
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