Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mortar Joint Deterioration in Masonry01:13

Mortar Joint Deterioration in Masonry

359
Mortar joint deterioration is a significant concern in masonry structures, with water accumulation in the joints leading to damage from freeze-thaw cycles. The repeated expansion of water during freezing and its melting during thawing develop and propagate cracks in the masonry joints. Eventually, this leads to the spalling of mortar from the joints, loosening masonry units and weakening the structure. The deteriorated mortar joints are also vulnerable to moisture intrusion into the walls.
The...
359
Serum Studies: Renal Function Tests01:24

Serum Studies: Renal Function Tests

457
Renal function tests are crucial for assessing kidney health, monitoring disease progression, and evaluating the kidneys' efficiency in waste elimination, fluid balance, and electrolyte regulation. These tests offer critical insights into kidney function, even though routine measurements may appear normal until there is a significant decline in the glomerular filtration rate or GFR. Typically, signs of kidney impairment only become evident when the GFR falls to about 50% of its normal level.
457
Poisson's Ratio01:23

Poisson's Ratio

1.3K
Poisson's ratio is a material property that indicates their stress response. It explains the connection between the elongation or compression a material undergoes in the direction of an applied force and the contraction or expansion it experiences perpendicular to that force. When a slender bar is loaded axially, it stretches in the direction of the force and contracts laterally. Poisson's ratio is the negative ratio of this lateral contraction to the axial elongation. The negative sign...
1.3K
Odds Ratio01:09

Odds Ratio

1.9K
The odds ratio (OR) is a statistical measure used extensively in epidemiology and research to quantify the strength of association between exposure and outcome across different groups. Unlike relative risk, which compares the probabilities of an event occurring, the odds ratio compares the odds of an event occurring in the exposed group to the odds of it occurring in the unexposed group. The odds, in this context, are calculated as the probability of the event happening divided by the...
1.9K
Hazard Ratio01:12

Hazard Ratio

627
The hazard ratio (HR) is a widely used measure in clinical trials to compare the risk of events, such as death or disease recurrence, between two groups over time. It reflects the ratio of hazard rates—the instantaneous risk of the event occurring—between a treatment group and a control group. This measure provides valuable insights into the relative effectiveness of a treatment by assessing how the risk of an event differs between the two groups.
For example, in a clinical trial...
627
Factors Affecting Renal Clearance: Renal Impairment01:17

Factors Affecting Renal Clearance: Renal Impairment

485
Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
485

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Serum sclerostin in biopsy-proven glomerulonephritis primarily reflects kidney function: a cross-sectional case-control study.

International urology and nephrology·2026
Same author

Variant histology in urothelial carcinoma: associated factors and survival impact after radical cystectomy.

BMC urology·2026
Same author

Safety and efficacy of percutaneous nephrolithotomy in elderly patients: a systematic review and meta-analysis by the EAU-YAU urolithiasis and EAU endourology sections.

World journal of urology·2026
Same author

CT-Derived Body Composition and Diet Quality in Kidney Transplant Recipients: A Single-Center Retrospective Cross-Sectional Study.

Medicina (Kaunas, Lithuania)·2026
Same author

Simulation based training versus mentorship in the initial learning curve of holmium laser enucleation of the prostate (HoLEP) surgery. The effects of simulation training on surgical success, complication rates, and surgeon workload: a prospective comparative study.

World journal of urology·2025
Same author

Evaluation of Body Image Perception in Patients Who Have Undergone Endoscopic Surgery for Kidney Stones: A Prospective Study.

Archivos espanoles de urologia·2025

Related Experiment Video

Updated: Feb 12, 2026

Transcutaneous Assessment of Renal Function in Conscious Rodents
07:18

Transcutaneous Assessment of Renal Function in Conscious Rodents

Published on: March 26, 2016

12.9K

Does neutrophil to lymphocyte ratio demonstrate deterioration in renal function?

Senol Tonyali1, Cavit Ceylan1, Sedat Yahsi1

  • 1a Clinic of Urology , Turkiye Yuksek Ihtisas Training and Research Hospital , Ankara , Turkey.

Renal Failure
|April 5, 2018
PubMed
Summary

The neutrophil-to-lymphocyte ratio (NLR) may serve as a practical indicator of chronic kidney disease (CKD) in patients post-nephrectomy. Elevated NLR correlates with reduced kidney function and advanced CKD stages.

Keywords:
Neutrophilchronic kidney diseaselymphocytenephrectomyrenal failure

More Related Videos

Author Spotlight: Balancing Speed, Cost, and Accuracy in Neutrophil Function Assessment with NeutroFun Screen Protocol
12:27

Author Spotlight: Balancing Speed, Cost, and Accuracy in Neutrophil Function Assessment with NeutroFun Screen Protocol

Published on: February 9, 2024

3.8K
Direct Drug Delivery to Kidney via the Renal Artery
11:18

Direct Drug Delivery to Kidney via the Renal Artery

Published on: April 17, 2021

8.3K

Related Experiment Videos

Last Updated: Feb 12, 2026

Transcutaneous Assessment of Renal Function in Conscious Rodents
07:18

Transcutaneous Assessment of Renal Function in Conscious Rodents

Published on: March 26, 2016

12.9K
Author Spotlight: Balancing Speed, Cost, and Accuracy in Neutrophil Function Assessment with NeutroFun Screen Protocol
12:27

Author Spotlight: Balancing Speed, Cost, and Accuracy in Neutrophil Function Assessment with NeutroFun Screen Protocol

Published on: February 9, 2024

3.8K
Direct Drug Delivery to Kidney via the Renal Artery
11:18

Direct Drug Delivery to Kidney via the Renal Artery

Published on: April 17, 2021

8.3K

Area of Science:

  • Nephrology
  • Inflammation markers
  • Surgical outcomes

Background:

  • Chronic kidney disease (CKD) is a significant global health concern, often leading to renal failure and cardiovascular complications.
  • Neutrophil-to-lymphocyte ratio (NLR) is recognized as a systemic inflammation marker, studied in various diseases including cardiovascular and vascular conditions.
  • Investigating NLR's role in assessing renal reserve and function post-nephrectomy is crucial for patient management.

Purpose of the Study:

  • To evaluate the neutrophil-to-lymphocyte ratio (NLR) as a potential indicator of renal reserve and function.
  • To determine the correlation between NLR and chronic kidney disease (CKD) status in patients who underwent nephrectomy.
  • To explore NLR's utility as a predictive marker for kidney function alongside traditional markers like creatinine.

Main Methods:

  • A retrospective study included patients undergoing radical/partial nephrectomy and those in urology/nephrology clinics.
  • Participants were categorized into four groups: healthy controls, post-partial nephrectomy, post-nephrectomy, and CKD patients.
  • Neutrophil-to-lymphocyte ratio (NLR) was measured and compared across groups, with correlation analysis against GFR and CKD stage.

Main Results:

  • Mean NLR was significantly higher in CKD patients (3.53 ± 2.30) compared to healthy controls (2.14 ± 0.73, p=0.005).
  • NLR showed a negative correlation with glomerular filtration rate (GFR) and a positive correlation with CKD stage (p=0.028).
  • NLR levels in post-nephrectomy groups were elevated but not significantly different from the CKD group.

Conclusions:

  • Neutrophil-to-lymphocyte ratio (NLR) may serve as a valuable and practical predictor of chronic kidney disease (CKD).
  • NLR could complement serum creatinine in assessing kidney function in patients following partial or radical nephrectomy.
  • Further research is warranted to establish NLR's role in routine clinical practice for CKD monitoring.