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The Collective Trust Game: An Online Group Adaptation of the Trust Game Based on the HoneyComb Paradigm
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Measuring trust in vaccination: A systematic review.

Heidi J Larson1,2, Richard M Clarke1, Caitlin Jarrett1,3

  • 1a Department of Infectious Disease Epidemiology , The Vaccine Confidence Project, London School of Hygiene & Tropical Medicine , Keppel Street, London WC1E 7HT , United Kingdom.

Human Vaccines & Immunotherapeutics
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PubMed
Summary

Public trust in vaccines is crucial. This review found vaccine research often implicitly addresses trust, with limited explicit examination and a need for more studies in low-income settings and on trust changes over time.

Keywords:
Trustconfidenceimmunization/immunisationvaccinationvaccines

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Area of Science:

  • Public Health
  • Health Communication
  • Social Science

Background:

  • Vaccine acceptance is contingent upon public trust in vaccines, healthcare systems, and professionals.
  • Understanding trust is vital for effective immunization programs and public health strategies.

Purpose of the Study:

  • To systematically review vaccine research literature that explicitly addresses the concept of trust.
  • To identify gaps in research regarding trust in vaccination contexts.

Main Methods:

  • Systematic review of 19,643 articles screened by title/abstract, with 35 included for full-text analysis.
  • Analysis of how trust is conceptualized and measured in vaccine research.
  • Examination of trust relationships relevant to vaccination.

Main Results:

  • Trust is often implicitly referenced (19/35 studies) rather than explicitly defined or discussed.
  • Quantitative trust measures were predominantly single-item (9/25 studies), with only two using validated multi-item scales.
  • Limited research exists on trust in low and middle-income settings and on how trust changes over time.

Conclusions:

  • A disconnect exists between vaccine hesitancy research and broader health trust literature.
  • There is a need for more research on trust dynamics in vaccination, particularly in diverse global settings and over time.
  • Future research should focus on building resilience to trust-eroding information within health systems.