Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genomics02:02

Genomics

40.9K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
40.9K
Movement Joints in Buildings01:27

Movement Joints in Buildings

361
Movement joints in buildings are essential design elements that accommodate inevitable motions caused by various factors such as temperature changes, moisture content variations, and structural deflections. These motions, if not considered in design and construction, can lead to unsightly or dangerous damage. Movement joints are incorporated in different forms to manage these stresses and allow materials to move without causing distress.
The simplest type of movement joints, working joints, are...
361
Types of Building Stone01:30

Types of Building Stone

464
Building stones, essential materials for construction, are extracted from natural rock deposits and processed into specific forms and dimensions suitable for various building applications. These stones are broadly classified into three types based on their geological formation: igneous, sedimentary, and metamorphic.
Igneous rocks are formed from the solidification of magma or lava. An example is granite, known for its durability and resistance to weathering, making it ideal for parts of...
464
Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

37.3K
Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
37.3K
Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

9.2K
While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.
9.2K
Design Example: Sustainability in Concrete Building01:26

Design Example: Sustainability in Concrete Building

426
As the construction industry moves towards more eco-friendly practices, concrete's adaptability and its ability to incorporate sustainable features make it a key material in the drive towards greener building solutions.
There are multiple approaches to achieve sustainability in a commercial concrete building. For instance, construct a concrete parking area under the building, utilizing pervious concrete paver blocks in open areas to facilitate rainwater collection through an underground...
426

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Frataxin deficiency drives cardiac dysfunction and transcriptional dysregulation in Friedreich ataxia iPSC model.

Cell death & disease·2026
Same author

Φ-Space ST: A platform-agnostic method to identify cell states in spatial transcriptomics studies.

Cell reports methods·2026
Same author

Scalable cell-specific coexpression networks for granular regulatory pattern discovery with NeighbourNet.

Genome research·2026
Same author

StableMate: a statistical method to select stable predictors in omics data.

NAR genomics and bioinformatics·2024
Same author

Stemformatics data portal enables transcriptional benchmarking of lab-derived myeloid cells.

Stem cell reports·2024
Same author

IsoVis - a webserver for visualization and annotation of alternative RNA isoforms.

Nucleic acids research·2024
Same journal

Biomedical Concept Recognition with Error-aware Negative-enhanced Ranking Framework.

Bioinformatics (Oxford, England)·2026
Same journal

TEDLH: Domain HMMs for sensitive detection of remote homologues.

Bioinformatics (Oxford, England)·2026
Same journal

PLNFGL: Joint Estimation of Multi-Condition Gene Networks from Single-cell RNA-seq Data.

Bioinformatics (Oxford, England)·2026
Same journal

MCFST: Spatial domain identification method based on multi-view graph convolutional network and graph fusion network.

Bioinformatics (Oxford, England)·2026
Same journal

SpaBiT: Enhancing Spatial Transcriptomics Resolution via Bidirectional Attention Transformers.

Bioinformatics (Oxford, England)·2026
Same journal

EDEL: Enhancing Dense Retrievers for Curation of Biomedical Knowledge Bases.

Bioinformatics (Oxford, England)·2026
See all related articles

Related Experiment Video

Updated: Feb 12, 2026

Methods to Test Visual Attention Online
09:44

Methods to Test Visual Attention Online

Published on: February 19, 2015

12.5K

Building online genomics applications using BioPyramid.

Liam Stephenson1, Yoshua Wakeham1, Nick Seidenman1

  • 1Division of Molecular Medicine, The Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.

Bioinformatics (Oxford, England)
|April 5, 2018
PubMed
Summary
This summary is machine-generated.

BioPyramid is a Python package for exploring gene expression data. It enables bioinformaticians to rapidly share interactive analyses and transformed data, offering a scalable solution beyond single-dataset tools.

More Related Videos

Analyzing and Building Nucleic Acid Structures with 3DNA
16:24

Analyzing and Building Nucleic Acid Structures with 3DNA

Published on: April 26, 2013

21.3K
Interactive and Visualized Online Experimentation System for Engineering Education and Research
08:35

Interactive and Visualized Online Experimentation System for Engineering Education and Research

Published on: November 24, 2021

3.0K

Related Experiment Videos

Last Updated: Feb 12, 2026

Methods to Test Visual Attention Online
09:44

Methods to Test Visual Attention Online

Published on: February 19, 2015

12.5K
Analyzing and Building Nucleic Acid Structures with 3DNA
16:24

Analyzing and Building Nucleic Acid Structures with 3DNA

Published on: April 26, 2013

21.3K
Interactive and Visualized Online Experimentation System for Engineering Education and Research
08:35

Interactive and Visualized Online Experimentation System for Engineering Education and Research

Published on: November 24, 2021

3.0K

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Genomics

Background:

  • Sharing 'omics' data for exploration is crucial in bioinformatics.
  • Existing R-based tools are often limited to small-scale, single-dataset solutions.
  • Bioinformaticians need efficient ways to collaborate on complex gene expression data.

Purpose of the Study:

  • To introduce BioPyramid, a Python package for building online applications.
  • To facilitate rapid sharing of transformed gene expression data and interactive analyses.
  • To provide a scalable and component-rich scaffold for bioinformatics web applications.

Main Methods:

  • Developed using the Python Pyramid framework.
  • Incorporates components for gene annotation, dataset modeling, and visualization.
  • Implemented in Python and JavaScript for web application development.

Main Results:

  • BioPyramid offers a scalable alternative to current R-based tools.
  • The package reduces development time for creating data exploration applications.
  • Provides essential components for building robust bioinformatics web tools.

Conclusions:

  • BioPyramid is a valuable tool for bioinformaticians to share and explore gene expression data.
  • Its scalable architecture supports both short-term and long-term complex projects.
  • Facilitates collaborative research through accessible interactive data analysis.