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Updated: Feb 12, 2026

Organotypic Slice Cultures as Preclinical Models of Tumor Microenvironment in Primary Pancreatic Cancer and Metastasis
Published on: June 22, 2021
Rare Metastasis of Primary Pancreatic Adenocarcinoma to the Bladder
Anup Shah1, Praneet Korrapati2, Jerome Siegel2
1Department of Medicine, Mount Sinai Beth Israel, New York, NY.
Abstract:
Pancreatic cancer commonly metastasizes to the liver, lungs, stomach, bone, and bowel, but rarely does it spread to the bladder. We describe a case of a 66-year-old woman with diabetes mellitus who presented with abnormal liver function laboratory tests, abdominal discomfort, unintentional weight loss, and no urinary symptoms. Abdominal CT revealed a pancreatic and bladder mass. Pathology of the bladder mass confirmed metastatic adenocarcinoma of pancreaticobiliary origin. To our knowledge, this is only the third case of metastatic pancreatic cancer spreading to the bladder since 1953.
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