A Changing Landscape in Cardiovascular Research Publication Output: Bridging the Translational Gap
Diane Gal1, Bart Thijs2, Wolfgang Glänzel3
1Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium.
Abstract:
The concern about predominance of basic discovery research and lack of translation into clinical medicine, and segregation between these research communities, led the authors to study these research communities through mapping networks of publications and cross-references. Cardiovascular research from 1993 to 2013 was published in 565 journals, including 104 new journals. Only 50% were published in core cardiovascular journals, such as the Journal of the American College of Cardiology, whereas one-half of cardiovascular publications were found in broader biomedical/multidisciplinary journals. The growth of the clinical journal community and merging into one broad journal community suggests a decreasing dichotomy between basic/preclinical and clinical research, potentially contributing to bridging the translational gap.
Related Concept Videos
Design Example: Strain Gauge Bridge or Wheatstone Bridge
Termination of Translation
Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of...
Gap Junctions
Gap Junctions
Wheatstone Bridge
Thus, for accurate resistance measurements, a...


