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Updated: Feb 12, 2026

In Vitro Analysis of Myd88-mediated Cellular Immune Response to West Nile Virus Mutant Strain Infection
Published on: November 27, 2014
Recent advances in understanding West Nile virus host immunity and viral pathogenesis
Huanle Luo1, Tian Wang1,2,3
1Department of Microbiology & Immunology, University of Texas Medical Branch, Galveston, USA.
Abstract:
West Nile virus (WNV), a mosquito-borne flavivirus, has been a significant public health concern in the United States for nearly two decades. The virus has been linked to acute viral encephalitis, neurological sequelae, and chronic kidney diseases. Neither antiviral drugs nor vaccines are currently available for humans. In vitro cell culture and experimental animal models have been used to study WNV infection in humans. In this review, we will focus on recent findings and provide new insights into WNV host immunity and viral pathogenesis.
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