Cluster headache: new targets and options for treatment
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Published on: June 2, 2014
Patty Doesborg1, Joost Haan1,2
1Department of Neurology, Leiden University Medical Center, Leiden, Netherlands.
Abstract:
Cluster headache is a severe headache disorder with considerable impact on quality of life. The pathophysiology of the disease remains poorly understood. With few specific targets for treatment, current guidelines mainly include off-label treatment with medication. However, new targets for possible treatment options are emerging. Calcitonin gene-related peptide (CGRP)-targeted medication could become the first (cluster) headache-specific treatment option. Other exciting new treatment options include invasive and non-invasive neuromodulation techniques. Here, we provide a short overview of new targets and treatment options that are being investigated for cluster headache.
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