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Published on: March 12, 2020
Recent trends in the structural revision of natural products
Bhuwan Khatri Chhetri1, Serge Lavoie, Anne Marie Sweeney-Jones
1School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332, USA. julia.kubanek@biosci.gatech.edu.
Abstract:
Covering: 2012 to 2017 This article reviews recent reports on the structural revision of natural products. Through a critical assessment of the original and revised published structures, the article addresses why each structure was targeted for revision, discusses the techniques and key discrepancies that led to the proposal of the revised structure, and offers measures that may have been taken during the original structure determination to prevent error. With the revised structures in hand, weaknesses of original proposals are assessed, providing a better understanding on the logic behind structure determination.
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