Related Experiment Video
Updated: Feb 12, 2026
11:48
Development of a Colloidal Gold-based Immunochromatographic Test Strip for Detection of Cetacean Myoglobin
Published on: July 13, 2016
14.8K
[Myoglobin: still a useful biomarker in 2017?]
Aurélie Servonnet1, Clément Dubost2, Guillaume Martin3
1Institut de recherche biomédicale des armées, Département des services, Unité analyses biologiques, Brétigny-sur-Orge, France.
Annales De Biologie Clinique
|April 7, 2018
Summary
Clinical biologists consult on biological tests. A literature review found limited clinical use for myoglobin assays, leading to the decision to discontinue the test.
Area of Science:
- Clinical Biology
- Medical Laboratory Science
- Diagnostic Testing
Background:
- Clinical biologists provide consultative services to optimize biological examination use.
- Medical laboratory advisory roles aid physicians in diagnosis and therapeutic strategies, preventing unnecessary tests.
- A review was conducted to assess the clinical utility of myoglobin assays.
Purpose of the Study:
- To evaluate the clinical relevance and indications for myoglobin assays.
- To determine if myoglobin assays offer significant diagnostic or prognostic value.
- To inform the decision regarding the continued performance of myoglobin assays in the laboratory.
Main Methods:
- Literature review of scientific articles and clinical guidelines.
- Analysis of the role of myoglobin assays in various medical conditions.
- Examination of current diagnostic criteria and scoring systems.
Main Results:
- Myoglobin assays have limited clinical indications.
- Myoglobin is not recommended in European guidelines for acute coronary syndromes without ST-segment elevation.
- Myoglobin is not a diagnostic or prognostic criterion for rhabdomyolysis and its role in predicting acute renal failure is debated; it's not included in recent scores like McMahon.
Conclusions:
- The clinical utility of myoglobin assays is minimal.
- Discontinuation of myoglobin assays is a justifiable decision based on current evidence.
- Optimizing laboratory test offerings enhances diagnostic efficiency and patient care.
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