Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Data Reporting and Recording01:24

Data Reporting and Recording

5.5K
Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.5K
Compact Bone01:27

Compact Bone

16.8K
Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
16.8K
Real Time RT-PCR02:57

Real Time RT-PCR

65.3K
Real-time reverse transcription-polymerase chain reaction, or Real-time RT-PCR, is an analytical tool used to determine the expression level of target genes. The method involves converting mRNA to complementary DNA with the help of an enzyme known as reverse transcriptase, followed by the PCR amplification of the cDNA. These two processes can be performed simultaneously in a single tube or separately as a two-step reaction.
The real-time quantification of the number of amplified products is...
65.3K
The Mantel-Cox Log-Rank Test01:19

The Mantel-Cox Log-Rank Test

1.1K
The Mantel-Cox log-rank test is a widely used statistical method for comparing the survival distributions of two groups. It tests whether a statistically significant difference exists in survival times between the groups without assuming a specific distribution for the survival data, making it a non-parametric test. This flexibility makes the log-rank test particularly valuable in medical research and other fields where the timing of an event, such as death or disease recurrence, is of...
1.1K
Compacting Factor test01:22

Compacting Factor test

606
The compacting factor test is a method used to assess the workability of concrete. It is  especially suitable for concrete mixes containing aggregates up to one and a half inches in size. This test involves specialized equipment consisting of two truncated cone-shaped hoppers and a cylinder, all with polished interior surfaces to minimize friction.
The procedure begins by placing concrete into the upper hopper without any compaction. Once filled, the bottom door of this hopper is opened,...
606
Neural Regulation01:37

Neural Regulation

43.5K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
43.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dosimetric Predictors of Problematic Receptive Anal Intercourse After Prostate Radiation Therapy.

Advances in radiation oncology·2026
Same author

In Reply to DeLaney.

International journal of radiation oncology, biology, physics·2026
Same author

Dosimetric Correlates of Acute Toxicities for Moderate Hypofractionated Whole-Breast Irradiation: Implications for ASTRO Planning Guidelines.

Advances in radiation oncology·2026
Same author

Neurogenic thoracic outlet syndrome secondary to an unilateral cervical rib in a poodle mix.

Journal of veterinary internal medicine·2026
Same author

Empirical oral AntibioticS for possible UTI in well appearing Young febrile infants (EASY).

NIHR open research·2026
Same author

Reirradiation Collaborative Group (ReCOG) consensus on standards for dose evaluation and reporting in patients with multiple courses of radiation therapy: an AAPM/ACRO/ASTRO/CARO/COMP/CADRA/CPQR/ESTRO/NRG-endorsed consensus statement.

The Lancet. Oncology·2026

Related Experiment Video

Updated: Feb 12, 2026

Optical Recording of Suprathreshold Neural Activity with Single-cell and Single-spike Resolution
08:48

Optical Recording of Suprathreshold Neural Activity with Single-cell and Single-spike Resolution

Published on: September 5, 2012

12.4K

Compact standalone platform for neural recording with real-time spike sorting and data logging.

Song Luan1, Ian Williams, Michal Maslik

  • 1EEE Department, Centre for Bio-Inspired Technology, Imperial College London, South Kensington Campus, London SW7 2BT, United Kingdom.

Journal of Neural Engineering
|April 7, 2018
PubMed
Summary

This study presents a compact headstage system for real-time neural data processing in awake, mobile animals. The system significantly reduces data bandwidth, enabling long-term, untethered brain-machine interface recordings.

More Related Videos

A Wireless, Bidirectional Interface for In Vivo Recording and Stimulation of Neural Activity in Freely Behaving Rats
10:41

A Wireless, Bidirectional Interface for In Vivo Recording and Stimulation of Neural Activity in Freely Behaving Rats

Published on: November 7, 2017

14.1K
A Visual Guide to Sorting Electrophysiological Recordings Using 'SpikeSorter'
10:31

A Visual Guide to Sorting Electrophysiological Recordings Using 'SpikeSorter'

Published on: February 10, 2017

11.6K

Related Experiment Videos

Last Updated: Feb 12, 2026

Optical Recording of Suprathreshold Neural Activity with Single-cell and Single-spike Resolution
08:48

Optical Recording of Suprathreshold Neural Activity with Single-cell and Single-spike Resolution

Published on: September 5, 2012

12.4K
A Wireless, Bidirectional Interface for In Vivo Recording and Stimulation of Neural Activity in Freely Behaving Rats
10:41

A Wireless, Bidirectional Interface for In Vivo Recording and Stimulation of Neural Activity in Freely Behaving Rats

Published on: November 7, 2017

14.1K
A Visual Guide to Sorting Electrophysiological Recordings Using 'SpikeSorter'
10:31

A Visual Guide to Sorting Electrophysiological Recordings Using 'SpikeSorter'

Published on: February 10, 2017

11.6K

Area of Science:

  • Neuroscience
  • Biomedical Engineering
  • Data Science

Background:

  • Studying neural network behavior and developing brain-machine interfaces (BMIs) requires longitudinal observation of neural activity in awake, mobile animals.
  • High-volume neural recordings generate massive datasets, necessitating offline processing for individual neuron analysis.
  • Current methods often limit real-time, untethered data acquisition and analysis.

Purpose of the Study:

  • To develop a compact system for real-time neural data processing in freely behaving animals.
  • To significantly reduce data bandwidth requirements for efficient storage and wireless transmission.
  • To enable long-term, untethered operation for unobtrusive neural monitoring.

Main Methods:

  • A two-phase headstage system was developed: initial offline template generation followed by untethered real-time template matching.
  • The system performs spike sorting and logs event-driven spike data to a micro-SD card.
  • It supports simultaneous logging of raw neural signals for validation and achieves low-power, per-channel operation.

Main Results:

  • The system successfully recorded 32 channels of neural data for over 24 hours, demonstrating robustness to power and storage interruptions.
  • Real-time, spike-sorted data with low latency and bandwidth reduction (2-3 orders of magnitude) was achieved.
  • Initial recordings in a non-human primate M1 showed consistent spike shapes and expected neural activity changes during behavior and sleep.

Conclusions:

  • The developed platform enables unobtrusive, real-time monitoring and processing of neural activity in untethered animals.
  • This system offers a robust, low-latency, low-bandwidth solution suitable for advanced applications like BMIs and closed-loop neuromodulation.
  • It represents a significant advancement in low-power neural recording technology for long-term data logging and wireless transmission.