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Trinitrophenyl-derivative of urinary trypsin inhibitor: a strong antifibrinolytic agent
Acta Haematologica
|January 1, 1987
Abstract:
A trinitrophenyl derivative of urinary trypsin inhibitor (TNP-UTI) was found to demonstrate approximately 50 times stronger antiplasmin fibrinolysis than the intact UTI. Almost no change in antitrypsin or antichymotrypsin activity occurred as a result of the UTI modification. TNP-UTI was also shown to be a strong inhibitor of nonplasmin mediated fibrinolysis.