Related Experiment Video
Updated: Feb 12, 2026

Use of a Video Scoring Anchor for Rapid Serial Assessment of Social Communication in Toddlers
Published on: March 14, 2018
Eph/ephrin family anchored on exosome facilitate communications between cells
Yao Zhao1, Lingyu Yin1, Haoliang Zhang1
1School of Medical Technology, Xuzhou Medical University, Xuzhou, Jiangsu 221000, China.
Abstract:
Interactions of Ephrins and Eph receptors at cell membranes play crucial role in boundary formation and axon guidance. Extracellular vesicles (EVs), such as exosomes, are formed by cells communicating with each other in paracrine or endocrine manner. Until now, it is thought that direct cell-cell contact is necessary for ephrin and Eph receptor signal transduction. In this review, we discuss recent data that indicate the existence of a novel Eph-ephrin family anchored exosome signaling pathway in long-range intercellular communication and provide evidence that this type of signaling elicits cellular responses in cancer cells, independent of juxtacrine interactions. We emphasize that exosome-anchored Eph/ephrin involves a variety of biological processes and transduction signals, which may serve as a potential diagnostic biomarker.
Related Concept Videos
Role of Ephrin-Eph Signalling in Intestinal Stem Cell Renewal
Communication
Gene Families
Occasionally these regions can be adapted to take on new roles within the organism, becoming novel genes...
Protein Families
The Anchoring-and-Adjustment Heuristic
Facilitated Transport

