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Updated: Feb 12, 2026

08:56
Fate Mapping of Human Embryonic Stem Cells by Teratoma Formation
Published on: August 1, 2010
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De Novo DNA Methylation: Marking the Path from Stem Cell to Neural Fate
1Neuroscience Institute, Department of Neuroscience and Physiology, NYU School of Medicine, New York, NY 10016, USA.
Cell Stem Cell
|April 7, 2018
Abstract:
DNA methylation is an epigenetic mark that plays pivotal roles in gene regulation, but its functions in neural fate decisions are poorly understood. In this issue of Cell Stem Cell, Ziller et al. (2018) show that the de novo methyltransferase Dnmt3a ensures efficient generation of motor neurons from stem cells.
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