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Published on: January 16, 2018
The Rules of Successful Speed Dating Are Complex, Even for Super-Enhancers
1Department of Cell Biology, Erasmus University Medical Center, Wytemaweg 80, 3015 CN Rotterdam, the Netherlands.
Abstract:
Super-enhancers (SEs) are important for regulating cell identity genes and oncogenes, but correctly assigning target genes to SEs is difficult. Recently in Cell Reports, Lopes Novo et al. (2018) map interactions between SEs and promoters and observe a significant rewiring of complex SE-promoter networks between different pluripotent states.
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