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Baby brain atlases.

Kenichi Oishi1, Linda Chang2, Hao Huang3

  • 1Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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|April 7, 2018
PubMed
Summary
This summary is machine-generated.

Creating comprehensive baby brain atlases is crucial for neuroscience research. Multiple atlases are needed to capture anatomical variations and disease-related changes in the developing infant brain.

Keywords:
Brain atlasEarly developmentInfantNeonatePrenatal exposurePreterm birth

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Area of Science:

  • Neuroscience
  • Developmental Neuroscience
  • Medical Imaging

Background:

  • The infant brain undergoes rapid neurodevelopment, making it a key area of neuroscience research.
  • Brain atlases, serving as 3D anatomical references, are essential tools for studying the developing brain.
  • Advancements in MRI technology facilitate the creation of high-resolution infant brain atlases.

Purpose of the Study:

  • To review current human infant brain MRI atlases and their roles in developmental neuroscience.
  • To discuss the limitations of single atlases in representing anatomical variability and disease-related changes.
  • To propose future directions for developmental neuroscience research and clinical applications using brain atlases.

Main Methods:

  • Review of existing literature on infant brain MRI atlases.
  • Discussion of the types and functionalities of current brain atlases.
  • Exploration of the potential of disease-based atlases.

Main Results:

  • Multiple high-resolution infant brain atlases are now available due to technological advancements.
  • A single atlas is insufficient to fully characterize anatomical variations and developmental changes.
  • Disease-based atlases offer potential for integrating clinical information with anatomical data.

Conclusions:

  • The development and utilization of diverse infant brain atlases are critical for advancing developmental neuroscience.
  • Future research should focus on creating multi-modal and disease-specific atlases.
  • Brain atlases have significant potential for clinical applications in understanding and diagnosing infant neurological conditions.