Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Trial and Error and Algorithm01:12

Trial and Error and Algorithm

429
A problem-solving strategy is a plan of action used to find a solution. Different strategies have distinct action plans. Trial and error involves trying different solutions until one works. For instance, to fix a broken printer, you might check ink levels, ensure the paper tray isn't jammed, and verify the printer's connection to your laptop. This method can be time-consuming but is commonly used. Thomas Edison, for example, used trial and error to find a suitable filament for the light...
429
Clinical Trials: Overview01:11

Clinical Trials: Overview

5.0K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
5.0K
Clinical Trials01:16

Clinical Trials

10.9K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
10.9K
Statistical Software for Data Analysis and Clinical Trials01:12

Statistical Software for Data Analysis and Clinical Trials

1.6K
Statistical software is pivotal in data analysis and clinical trials by providing tools to analyze data, draw conclusions, and make predictions. These software packages range from simple data management applications to complex analytical platforms, supporting various statistical tests, models, and simulation techniques. Their significance lies in their ability to handle vast amounts of data with precision and efficiency, enabling researchers to validate hypotheses, identify trends, and make...
1.6K
Uterine Tubes01:16

Uterine Tubes

2.5K
The uterine or fallopian tubes function as the conduit through which oocytes travel from the ovaries to the uterus. Each fallopian tube measures approximately 10 to 13 cm long and is anatomically divided into the infundibulum, ampulla, isthmus, and interstitial part (or intramural segment). The infundibulum is characterized by its funnel shape and features extensions called fimbriae which reach towards the peritoneal cavity. These fimbriae play a critical role during ovulation as they extend...
2.5K
Random Error01:04

Random Error

9.8K
Random or indeterminate errors originate from various uncontrollable variables, such as variations in environmental conditions, instrument imperfections, or the inherent variability of the phenomena being measured. Usually, these errors cannot be predicted, estimated, or characterized because their direction and magnitude often vary in magnitude and direction even during consecutive measurements. As a result, they are difficult to eliminate. However, the aggregate effect of these errors can be...
9.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spin-correlations and magnetic structure in an Fe monolayer on 5d transition metal surfaces.

Journal of physics. Condensed matter : an Institute of Physics journal·2014
Same author

Cryosclerosis. A forgotten endovenous procedure for treating the incompetence of the great saphenous vein. Short term results.

International angiology : a journal of the International Union of Angiology·2014
Same author

[Nasal dermal sinus in children: a review based on a series of 6 cases].

Neuro-Chirurgie·2014
Same author

Alternatives approaches to the sub-occipital transtentorial route for pineal tumors: How and when I do it?

Neuro-Chirurgie·2014
Same author

Nutritional differences between a gluten-free diet and a diet containing equivalent products with gluten.

Plant foods for human nutrition (Dordrecht, Netherlands)·2014
Same author

Incidence of occult contralateral carcinomas of the breast following mastoplasty aimed at symmetrization.

Annales de chirurgie plastique et esthetique·2014

Related Experiment Video

Updated: Feb 12, 2026

Enumeration of Major Peripheral Blood Leukocyte Populations for Multicenter Clinical Trials Using a Whole Blood Phenotyping Assay
14:45

Enumeration of Major Peripheral Blood Leukocyte Populations for Multicenter Clinical Trials Using a Whole Blood Phenotyping Assay

Published on: September 16, 2012

15.5K

[Lower Uterine Segment Trial: A pragmatic open multicenter randomized trial].

P Rozenberg1, P Deruelle2, M-V Sénat3

  • 1Département d'obstétrique et gynécologie, centre hospitalier Poissy-Saint-Germain, rue du Champ-Gaillard, 78303 Poissy cedex, France; Unité de recherche EA7285, université Versailles-St-Quentin, Montigny-le-Bretonneux, France.

Gynecologie, Obstetrique, Fertilite & Senologie
|April 8, 2018
PubMed
Summary

Ultrasound measurement of lower uterine segment (LUS) thickness can guide delivery decisions for women with prior cesarean. This may reduce maternal and fetal complications associated with trial of labor versus repeat cesarean delivery.

Keywords:
Cesarean deliveryCésarienneDéhiscence utérineRupture utérineTentative de voie basseTrial of laborUltrasonUltrasonographyUltrasoundUterine dehiscenceUterine ruptureÉchographie

More Related Videos

Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain
03:26

Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain

Published on: March 8, 2024

3.6K
Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment
08:36

Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment

Published on: April 19, 2024

1.2K

Related Experiment Videos

Last Updated: Feb 12, 2026

Enumeration of Major Peripheral Blood Leukocyte Populations for Multicenter Clinical Trials Using a Whole Blood Phenotyping Assay
14:45

Enumeration of Major Peripheral Blood Leukocyte Populations for Multicenter Clinical Trials Using a Whole Blood Phenotyping Assay

Published on: September 16, 2012

15.5K
Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain
03:26

Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain

Published on: March 8, 2024

3.6K
Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment
08:36

Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment

Published on: April 19, 2024

1.2K

Area of Science:

  • Obstetrics and Gynecology
  • Maternal-Fetal Medicine
  • Diagnostic Ultrasound

Background:

  • Trial of labor and elective repeat cesarean delivery after a prior cesarean delivery carry significant, yet uncertain, risks and benefits for both mother and fetus.
  • High-level evidence quantifying these risks is scarce, complicating informed counseling.
  • Ultrasound measurement of the lower uterine segment (LUS) thickness shows promise in assessing scar integrity and predicting uterine defects.

Purpose of the Study:

  • To evaluate the efficacy of ultrasound measurement of LUS thickness in guiding delivery decisions for women with a prior cesarean delivery.
  • To determine if this approach can reduce fetal and maternal morbidity and mortality.
  • To provide evidence for establishing clinical recommendations regarding delivery management after cesarean.

Main Methods:

  • A pragmatic, open, multicenter randomized trial with two parallel arms.
  • Women with a prior low transverse cesarean delivery (36-38 weeks gestation) were randomized.
  • The study group received LUS thickness ultrasound measurements to guide delivery recommendations (threshold of 3.5mm), while the control group followed standard practice.

Main Results:

  • The primary composite outcome included uterine rupture, dehiscence, hysterectomy, thromboembolic complications, transfusion, endometritis, and maternal, fetal, and neonatal mortality.
  • Ultrasound assessment of LUS thickness demonstrated a strong correlation with intraoperative findings and excellent negative predictive value for uterine defects.
  • A thinner LUS on ultrasound was associated with a higher likelihood of uterine defects.

Conclusions:

  • Ultrasound measurement of LUS thickness can potentially aid in risk stratification for women with a prior cesarean delivery.
  • This method may help reduce elective repeat cesarean deliveries and associated fetal and maternal complications.
  • Further evidence from this trial will inform clinical recommendations for optimizing delivery modes after cesarean.