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Updated: Feb 12, 2026

Bead Loading Proteins and Nucleic Acids into Adherent Human Cells
Published on: June 1, 2021
Carb loading takes proteins on a ride
Christina Schäffer1, Paul Messner2
1From the Department of NanoBiotechnology, NanoGlycobiology Unit, Universität für Bodenkultur Wien, A-1190 Vienna, Austria christina.schaeffer@boku.ac.at.
Abstract:
Cytoplasmic protein O-glycosylation in bacteria is often required for protein maturation, but the dependence of protein export on carbohydrate modifications is less understood. In the current issue of JBC, Chen et al. describe the mechanism for posttranslational modification of a Streptococcus gordonii adhesin and its delivery to the membrane, leading to the first comprehensive model featuring the interplay of glycosyltransferases and the translocation system.
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