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Related Experiment Video

Updated: Feb 12, 2026

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins

Published on: June 11, 2015

High-throughput mouse phenomics for characterizing mammalian gene function.

Steve D M Brown¹, Chris C Holmes², Ann-Marie Mallon³

¹MRC Harwell Institute, Harwell, UK. S.brown@har.mrc.ac.uk.

Nature Reviews. Genetics

|April 8, 2018

Summary

This summary is machine-generated.

Mouse phenomics is advancing with large-scale mutant generation and comprehensive phenotyping. This generates valuable gene-phenotype data, aiding in understanding mammalian gene function and disease models.

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Last Updated: Feb 12, 2026

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins

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Published on: June 11, 2015

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Using Mouse Oocytes to Assess Human Gene Function During Meiosis I

Using Mouse Oocytes to Assess Human Gene Function During Meiosis I

Published on: April 10, 2018

Area of Science:

Genomics and Mammalian Biology
Bioinformatics and Computational Biology

Background:

The field of mouse phenomics is rapidly evolving.
Advances in generating mouse mutants and phenotyping techniques are crucial.

Purpose of the Study:

To highlight the significance of large-scale mouse phenomics studies.
To emphasize the utility of phenome resources for understanding gene function and disease.

Main Methods:

Economical generation of mouse mutants.
Sophisticated and comprehensive phenotyping techniques.
Integration of multidimensional gene-phenotype data sets.

Main Results:

New insights into the mammalian genome landscape.
Discovery of previously unknown mammalian gene functions.
Establishment of valuable disease models.

Conclusions:

Phenome resources are powerful tools for interpreting human genetic variation and disease relationships.
Future advancements in phenotyping platforms and computational approaches (e.g., machine learning) will enhance the modeling of mammalian gene-phenotype space.