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Updated: Feb 12, 2026

Isolation of Sertoli Cells and Peritubular Cells from Rat Testes
Published on: February 8, 2016
Prepubertal Malignant Large Cell Calcifying Sertoli Cell Tumor of the Testis
Guanqun Li1, Matthew S Lee2, Kate H Kraft2
1State University of New York Upstate Medical University, Syracuse, NY.
Abstract:
An otherwise healthy 7-year-old boy was diagnosed with malignant large cell calcifying Sertoli cell tumor (LCCSCT) of the testis. He underwent attempted partial orchiectomy with conversion to radical orchiectomy due to suspected malignancy on intraoperative frozen section. There was no lymph node or visceral metastases. To our knowledge, this is the first report of malignant LCCSCT in the prepubertal population. LCCSCT of the testis is an extremely rare neoplasm, with low malignant potential. Malignant cases are exclusively reported previously in the adult population. We report the first case of malignant LCCSCT in a pediatric patient. We review the literatures and discuss the clinical, pathologic features and treatments of malignant LCCSCT.
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