Related Experiment Video
Updated: Feb 12, 2026
Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering
Published on: July 27, 2022
Synthesis and characterization of chitosan modified polyurethane bio-nanocomposites with biomedical potential
Muhammad Asif Javaid1, Rasheed Ahmad Khera1, Khalid Mahmood Zia2
1Department of Chemistry, University of Agriculture, Faisalabad 38040, Pakistan.
Abstract:
A series of chitosan (CS) and montmorillonite (MMT) clay based polyurethane bio-nanocomposites were synthesized by step growth polymerization; reacting hydroxyl terminated polybutadiene (HTPB) and toluene diisocyanate (TDI) to improve thermal and antibacterial properties of polyurethane (PU). Five different PU samples were prepared by varying mole ratio of CS and 1,4-butane diol (from 0 to 2 mol). Structural studies of PUs through FTIR and 1H NMR spectroscopy confirmed the incorporation of CS into the polymer matrix. The scanning electron microscope (SEM) analysis confirmed well dispersion of MMT clay into the PU matrix. Thermogravimetric analysis (TGA) of PUs indicated significant enhancement of thermal stability of PU with addition of CS. Antibacterial properties of PUs were measured by disc diffusion method; showed excellent potential against the selected strains. On the whole, CS showed potential to improve the antibacterial and structural properties of PU significantly; which might be precursor for biological applications.
Related Concept Videos
02:36Transfer RNA Synthesis
Each of these chemical modifications is carried by a specific enzyme, post-transcription. All of these enzymes have unique base and site-specificity. Methylation, the most common chemical modification, is carried by at least nine different enzymes, with...
01:15Dehydration Synthesis
Dehydration synthesis (also called a condensation reaction) is the chemical process in which two molecules covalently link together to form a new molecule, along with the release of a water molecule. Many physiologically important compounds form by dehydration synthesis reactions, such as complex carbohydrates, proteins, DNA, and RNA.
Synthesis of carbohydrates
Sugar molecules are covalently linked together by dehydration synthesis. During the reaction, the hydroxyl (-OH) group from...
02:17Synthesis and Decomposition Reactions
01:59Lagging Strand Synthesis
There are several major differences between synthesis of the leading strand and synthesis of the lagging strand. 1) Leading strand synthesis happens in the direction of replication fork opening, whereas lagging strand synthesis happens in the...
00:52Potential Energy
Chemical bonds that form attractive forces between atoms also contain potential energy, called chemical energy. When a chemical reaction...
02:53Ribosomal RNA Synthesis
Ribosome biogenesis begins with the synthesis of 5S and 45S pre-rRNAs by distinct RNA polymerases. The primary transcripts are extensively processed and modified before they are bound and folded by ribosomal proteins and assembly factors,...