The value of shear wave elastography in diffuse thyroid disease
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Updated: Feb 12, 2026

Application of Ultrasound and Shear Wave Elastography Imaging in a Rat Model of NAFLD/NASH
Published on: April 20, 2021
Jianxue Liu1, Yaoren Zhang2, Yonghao Ji2
1Department of Infectious Disease, The First Affiliated Hospital of Medical College, Xi'an Jiaotong University, Shaanxi 710061, China; Department of Ultrasonography, Baoji Central Hospital, Baoji 721008, China.
Purpose:
The aim of this study is to discuss the value of ultrasound-based shear wave™ elastography (SWE) in diffuse thyroid disease (DTD).
Method:
Thyroid stiffness in 154 patients with DTD and 30 normal subjects was measured by SWE. The serum indicators of all subjects were detected.
Results:
The area under the receiver operating characteristic (AUROC) curve for DTD by SWE was 0.852. The AUROCs of SWE for differentiating chronic autoimmune thyroiditis (CAT) from Graves' disease (GD) and subacute thyroiditis (SAT) were 0.549 and 0.989, respectively. The AUROCs for distinguishing GD from SAT by SWE and the fT3/fT4 ratio were 0.975 and 0.713, respectively.
Conclusion:
SWE aids in the diagnosis of DTD, and SWE is superior to the fT3/fT4 ratio for distinguishing GD from SAT. However, SWE was unsuitable for differentiating CAT from GD.
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