Endovascular recanalisation with drug coated balloon for chronic symptomatic middle cerebral artery total occlusion

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Focal Cerebral Ischemia Model by Endovascular Suture Occlusion of the Middle Cerebral Artery in the Rat
13:50

Focal Cerebral Ischemia Model by Endovascular Suture Occlusion of the Middle Cerebral Artery in the Rat

Published on: February 5, 2011

81.0K

Jun Zhang1, Xiao Zhang1, Jin-Ping Zhang1

  • 1Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, China.

Journal of Neurointerventional Surgery
|April 9, 2018
PubMed

Insights

Drug-coated balloons (DCBs) offer a promising treatment for chronic middle cerebral artery (MCA) total occlusion. This case report shows successful revascularization and a good one-year outcome, suggesting DCBs as a viable option.

Area of Science:

  • Neurology
  • Interventional Neuroradiology
  • Vascular Surgery

Background:

  • Optimal treatment for chronic symptomatic middle cerebral artery (MCA) total occlusion remains unclear.
  • Stenting shows promise for revascularization but carries a high risk of in-stent restenosis (ISR).
  • Drug-coated balloons (DCBs) are effective for ISR but their use in de novo intracranial stenosis, particularly total occlusions, is not well-established.

Observation:

  • A patient with chronic left MCA total occlusion was treated using DCBs.
  • The procedure aimed to address de novo atherothrombotic stenosis.

Findings:

  • Successful revascularization of the total MCA occlusion was achieved with DCBs.
  • The patient demonstrated a good clinical outcome at the one-year follow-up.

Implications:

  • DCBs may be a feasible treatment option for de novo intracranial atherothrombotic stenosis, including total occlusions.
  • Further comparative studies are needed to evaluate DCBs against stenting for intracranial revascularization.
  • This approach could offer an alternative for patients at risk of ISR.

Keywords:
angioplastyballoonstenosis

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