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Updated: Feb 12, 2026

Growing a Cystic Fibrosis-Relevant Polymicrobial Biofilm to Probe Community Phenotypes
Published on: April 19, 2024
Cystic fibrosis pathogens survive for extended periods within cough-generated droplet nuclei
Michelle E Wood1,2,3, Rebecca E Stockwell1,3, Graham R Johnson4
1Lung Bacteria Group, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.
Abstract:
The airborne route is a potential pathway in the person-to-person transmission of bacterial strains among cystic fibrosis (CF) populations. In this cross-sectional study, we investigate the physical properties and survival of common non-Pseudomonas aeruginosa CF pathogens generated during coughing. We conclude that Gram-negative bacteria and Staphylococcus aureus are aerosolised during coughing, can travel up to 4 m and remain viable within droplet nuclei for up to 45 min. These results suggest that airborne person-to-person transmission is plausible for the CF pathogens we measured.
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