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Regulatory sites of cationic nature on skeletal myosin
M J López-Zabalza1, M S Laborda-Santesteban, M B Garrido-Garrido
1Department of Biochemistry, University of Navarra, Pamplona, Spain.
Abstract:
The kinetics of the Ca2+-ATPase of chicken skeletal myosin has been found to be of a biphasic type. DNP and SCN- increased Ca2+-ATPase activity, whereas CN- and HCO3- acted as inhibitors in the concentration range used. Upon raising substrate concentration, activation and inhibition constants for those modifiers responded also with an elevation of their values.