Invasive fungal infection in immunocompetent trauma patients - A case series

Senthil Loganathan1, Gowtham A E Ajay1, U Thyagarajan1

  • 1Department of Orthopaedics, Sri Ramachandra University, India.

Insights

Trauma can lead to angioinvasive zygomycosis, a severe fungal infection, even in healthy individuals. This study highlights the high mortality rate and the critical role of amputation in survival for these rare cases.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Trauma Surgery

Background:

  • Zygomycosis is a severe invasive fungal infection, ranking third after candidiasis and aspergillosis.
  • While typically affecting immunocompromised individuals, trauma can precipitate zygomycosis in immunocompetent hosts.
  • Angioinvasion in zygomycosis leads to a high mortality rate, approximately 50%.

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