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Fixed cutaneous sporotrichosis, a fungal infection, should be considered in diabetic patients with non-healing ulcers. This case highlights successful treatment with itraconazole in an immunocompromised individual.

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Area of Science:

  • Medical Mycology
  • Dermatology
  • Infectious Diseases

Background:

  • Fixed cutaneous sporotrichosis is a rare fungal infection caused by *Sporothrix schenckii*.
  • It can present as a differential diagnosis in diabetic patients with non-healing ulcers, particularly those who are immunocompromised.
  • The infection is often associated with minor trauma, such as animal bites.

Purpose of the Study:

  • To report a case of fixed cutaneous sporotrichosis in a diabetic patient.
  • To emphasize the importance of considering this diagnosis in immunocompromised individuals with chronic skin lesions.
  • To illustrate the efficacy of oral itraconazole in treating this condition.

Main Methods:

  • A case report of a 70-year-old male with diabetes mellitus and a non-healing finger ulcer.
  • Diagnosis confirmed by skin biopsy identifying *Sporothrix schenckii*.
  • Treatment initiated with empirical oral itraconazole (200 mg twice daily).

Main Results:

  • The patient presented with a 1-month history of an unhealed ulcer on his left middle finger following a cat bite.
  • Skin biopsy confirmed *Sporothrix schenckii* infection.
  • Significant improvement of the skin lesion was observed after 2 months of itraconazole therapy.

Conclusions:

  • Fixed cutaneous sporotrichosis is a treatable condition that warrants consideration in diabetic patients with non-healing ulcers.
  • Early diagnosis and appropriate antifungal therapy, such as itraconazole, are crucial for successful outcomes.
  • This case underscores the potential for *Sporothrix schenckii* infection in immunocompromised individuals, even with seemingly minor exposures.