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Published on: October 25, 2024
Spinal infections in children: a multicentre retrospective study.
R Dayer1, M M Alzahrani2, N Saran3
1Division of Paediatric Orthopaedics, University Hospitals of Geneva, 6 Rue Willy Donzé, 1211 Geneva 14, Switzerland.
Primary pyogenic spinal infections in children are more common in males. Methicillin-sensitive Staphylococcus aureus (MSSA) and Kingella kingae are key pathogens, particularly in young children.
Area of Science:
- Pediatric infectious diseases
- Orthopedic surgery
- Microbiology
Background:
- Primary pyogenic spinal infections in children are rare but serious conditions.
- Understanding epidemiological and etiological factors is crucial for effective management.
Purpose of the Study:
- To enhance knowledge of pediatric primary pyogenic spinal infections.
- To analyze a large consecutive case series for epidemiological and microbiological insights.
Main Methods:
- Retrospective analysis of medical records from 103 children treated between 2004 and 2014.
- Evaluation of epidemiological, clinical, paraclinical, radiological, and microbiological data.
Main Results:
- A male predominance (65%) was observed.
- The lumbar spine, particularly L4/5, was the most affected region.
- Methicillin-sensitive Staphylococcus aureus (MSSA) and Kingella kingae were the most common pathogens.
Conclusions:
- MSSA is a primary pathogen, while K. kingae is significant in children aged 6 months to 4 years.
- Empirical antibiotic protocols should consider age distribution and specific bacteriology.
- Further prospective studies are needed to validate findings and explore diagnostic tools like PCR for K. kingae.
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