Related Experiment Video
Updated: Feb 12, 2026

Measuring Progressive Neurological Disability in a Mouse Model of Multiple Sclerosis
Published on: November 14, 2016
ECTRIMS/ACTRIMS 2017: Closing in on neurorepair in progressive multiple sclerosis
David Kremer1, Patrick Küry1, Hans-Peter Hartung1
1Department of Neurology, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Background:
While there is now a multitude of potent medications for relapsing-remitting multiple sclerosis (RRMS), effective therapies targeting neurodegeneration in progressive multiple sclerosis types are still lacking. Stimulation of neurorepair in this disease remains a pathogenetically defined treatment goal. However, therapeutic progress is slowed by the still inadequate tool set to capture "regeneration/repair" in MS and to define appropriate outcomes in clinical trials.
Objectives:
In this review, we discuss studies investigating promising regenerative agents for progressive MS which were recently presented during the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS)/Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) 2017 meeting in Paris.
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